Researchers for five years conducted an experiment involving more than 19 thousand people in Australia and the United States. The average age of the subjects was 74 years, while they were healthy, did not suffer from cardiovascular disease or dementia. Half of them took 100 mg of aspirin daily (acetylsalicylic acid), and the rest received a placebo.
It turned out that there were no significant differences in the frequency of deaths, disabilities or the development of dementia between the participants in the experiment: scientists recorded 21.5 such cases per thousand subjects per year in the first group and 21.2 in the second. However, the risk of serious bleeding among those who received aspirin was 3.8% versus 2.8% in those taking placebo.
Thus, the researchers concluded that taking aspirin by healthy elderly people for five years did not extend life expectancy and led to an increase in the number of serious bleeding.
It is noted that aspirin is often used to reduce the recurrence of cardiovascular disease in people aged who have undergone coronary insufficiency. This drug reduces platelet aggregation, which reduces the risk of blockage of blood vessels, however, it can provoke bleeding in the brain and gastrointestinal tract, RIA Novosti writes.
Danish scientists have found that taking diclofenac increases the risk of fatal diseases by 50%. The British publication Which?, Which specializes in checking the quality of consumer goods and services, has published a list of the most dangerous foods and food additives that can cause cancer.
Healthy heart - risk free life
Previously, salicylic acid was obtained from plant materials - spirea shrubs. Then, an acetyl (acetic) radical was added to the pain medication. Taking the prefix a-and from spiraea, the root -spir- from acetyl, we received the familiar name A-spir-in. But, despite the fact that Aspirin has been well studied and known for a long time, many buyers do not even realize its valuable properties. For example, that Aspirin saves millions of lives every day. To find out the truth about this medicine, you must first dispel the most common myths.
Aspirin is used only for pain and heat.
Aspirin is familiar to everyone - it is one of the most famous and widely used medicines, with more than 100 years of history. And indeed, with pain and temperature, millions of people all over the world are turning to Aspirin for salvation. But this drug is also widely used in cardiology to prevent the development of cardiovascular disease (CVD). The antiplatelet effect of Aspirin is to block the cyclooxygenase (COX) enzyme and to reduce the production of thromboxane, a type of prostaglandin that causes blood cells (platelets) to “stick together” with each other. When suppressing the production of prostaglandins, the pain signal is not transmitted, the temperature and inflammatory response does not develop, and it is the suppression of prostaglandin synthesis that is associated with the traditional properties of Aspirin, analgesic, antipyretic and anti-inflammatory. These properties of Aspirin are most pronounced in Aspirin at a dose of 500 mg. In addition, with a decrease in the level of prostaglandins, platelet activity decreases. In other words, under the influence of Aspirin, blood liquefies, the risk of blood clots, and therefore complications of coronary heart disease, heart attacks and strokes, is reduced. The antiplatelet effect of Aspirin lasts throughout the life of platelets for 7-10 days. This effect is optimally achieved by Aspirin in small doses - 100 mg.
Aspirin should not be taken in patients with arterial hypertension.
There are two types of strokes: some are caused by blood clots, and doctors call them ischemic strokes, the second reason is the rupture of blood vessels and the release of blood into the brain. Therefore, they are called cerebral hemorrhage or hemorrhagic strokes. Acetylsalicylic acid was suspected in the development of the latter. However, the results of studies on primary and secondary prevention of CVD have shown that the use of Aspirin with the right antihypertensive therapy does not increase the risk of cerebral hemorrhage and hemorrhagic stroke. It is possible and even necessary to prescribe antiplatelet drugs to patients with arterial hypertension. It is important that the patient has controlled hypertension, i.e. reached target levels: maintaining pressure at the level of 140/90 mm Hg. Art. and lower in patients with arterial hypertension, 130/80 mm RT. Art. - in people with diabetes.
All acetylsalicylic acid preparations are the same.
This is not true. For primary and secondary prevention of CVD, Bayer Schering Pharma has issued a special cardiological form, Aspirin Cardio, which has a number of fundamental differences from other acetylsalicylic acid preparations. The clinical efficacy, safety and high quality of Aspirin Cardio are confirmed by the results of large international studies. This circumstance has allowed many European and Russian medical organizations to call it the "gold standard" in the treatment of CVD. The original Bayer Schering Pharma drug has two dosages - 100 mg and 300 mg. The first is recommended for the prevention of CVD and their complications. A dose of 300 mg is necessary in critical situations, as well as in patients who have recently suffered an acute myocardial infarction or stroke. In addition, the striking difference of Aspirin Cardio is its enteric-soluble form, which minimizes possible side effects.
Aspirin can not be taken regularly and for a long time.
Indeed, many patients are afraid to take acetylsalicylic acid preparations regularly, because fear the development of side effects. In this regard, Bayer Schering Pharma has developed a special enteric-soluble form of Aspirin Cardio tablets. Acid-resistant membrane significantly improves tolerance of the drug, in particular, it reduces the risk of side effects from the gastrointestinal tract. Moreover, a dose of 100 mg is considered safe and is recommended by the European Society of Cardiology for long-term use in order to prevent cardiovascular events. Patients should be aware that discontinuation of antiplatelet drugs, in particular, leads to an increase in the number of cardiovascular complications. And first of all, this applies to patients at risk.
Aspirin Cardio prophylaxis effective only in men
In fact, the appointment of Aspirin Cardio is required for both men and women with moderate or high risk of CVD who have already suffered an ischemic stroke or heart attack. And the myth about the effectiveness of the drug exclusively in relation to the stronger sex is generated by the fact that until recently, the effectiveness of the drug in primary prevention was established only in men. Reliable information on the benefits of Aspirin Cardio in women simply did not exist. In 2005, the results of a large randomized study (Women's Health Study) were published, which proved the effectiveness of Aspirin Cardio in the primary prevention of vascular events in healthy women, especially those over the age of 65. The positive effect of the drug in prevention in women is associated with a decrease in the risk of stroke, while in men it is associated with a decrease in the likelihood of myocardial infarction. These results are consistent with evidence that the ratio of stroke to myocardial infarction in women is higher than in men.
100 mg / 300 mg
A simple rule: 1 tablet per day. Fasting with half a glass of water