Psoriasis is one of the most mysterious and poorly treatable diseases. It is impossible to get rid of him once and for all. The only thing that patients can count on is to achieve a stable remission. Moreover, a single and universally accepted methodology for treating psoriasis by the world medical community does not exist, nor is there a drug that guarantees the onset of remission.
The tactics of treating this complex skin disease depends on a number of parameters:
The presence of concomitant pathologies,
The severity and chronology of exacerbations,
Localization and size of lesions.
The treatment of psoriasis is almost always complex: part of the medications and procedures are aimed at eliminating the very cause of psoriatic exacerbations, part is designed to alleviate the unpleasant symptoms of the disease, and part is needed to maintain the body's own defenses. The sad thing is that almost half of the patients do not help any of the three approaches to the treatment of psoriasis. And that drug, which allowed thousands of people to drive psoriasis into a stable remission for several years, may very likely have no effect on another thousand.
In this article, we will discuss all currently known means and methods of treating psoriasis, even the most controversial ones, and try to answer the question of where to start a person who has heard a disappointing diagnosis from a doctor. During the use of popular methods, procedures and medicines, it was possible to collect impressive statistics of their effectiveness. We suggest that you familiarize yourself with patient reviews and find out how many percent of respondents really helped a particular psoriasis treatment.
Comparative analysis of the effectiveness of psoriasis treatment methods
According to the results of numerous surveys of people suffering from psoriasis, the hit parade of the best methods of treating this disease looks something like this:
Biological preparations - more than 33% of patients completely cleanse their skin in 3 months of therapy (the cost of a course of treatment is from $ 20,000 and above),
37% - Ointments based on solidol (Cytopsor, Kartalin, Acrustal, Magnipsor, Antipsor),
33% - Compliance with a special diet - that is, the rejection of foods whose use provokes exacerbations of psoriasis,
26% - Climate change, balneotherapy and spa treatment. Almost a third of patients report improvement in well-being simply in connection with moving to a place where there is a mild maritime climate and clean air. The same number of patients avoid winter exacerbation helps annual rest in the sanatorium.
Here is a list of the best profile resorts:
Sulfide mineral waters: Pyatigorsk, Yeysk, Kayakent, Kemeri, Khilovo, Goryachiy Klyuch, Sochi, Matsesta, Taminsk, Usolye, Krasnousolsk, Black waters, Sergievsky mineral waters, Transcarpathian Bruise,
Radon mineral waters: Belokurikha, Molokovka, Mironovka, Khmelnik, Zhytomyr, Tskhaltubo, Pyatigorsk, Krasnousolsk, Nilova Pustyn.
Sodium chloride mineral waters: Druskininkai, Kuldur, Ust-Kut, Angara, Sosonovsky Minvody, Lake Uchum, Lake Shira.
Mineral water: Odessa, Yevpatoriya, Saki, Berdyansk, Lake Elton.
Healing mud - Anapa, Yevpatoriya, Kurya, Lyuben-Veliky, Kayakent, Yeysk, Kemeri, Saki, Klyuchi, Lake Elton, Lake Uchum.
Children's sanatoriums: “Lenin Rocks” in Pyatigorsk, “Falcon” in Anapa, “Red Assault and Sanatorium named after N. A. Semashko in Sochi,
19% - Salt baths - are very effective both in the framework of spa treatment, and as home treatments.Sea salt contains potassium, magnesium, iodine and other useful minerals that have beneficial effects on the skin affected by psoriasis, relieve itching and peeling, and even improve the patient's sleep due to the relaxing effect on nerve endings. It is recommended to purchase in the pharmacy high-quality, natural sea salt and take baths 2-4 times a week at night,
14% - Tar-based ointments (Colloidin, Anthraminum and Antrasulfonovaya ointment) - well relieve itching, contribute to scarring of psoriatic plaques and falling off the crusts,
12% - Selective phototherapy (SFT) is a physiotherapeutic method of treating psoriasis, based on the therapeutic effect of ultraviolet radiation with a specific wavelength on the skin. It is by no means suitable for all patients, but for some it allows for 1.5-2 months of regular procedures to achieve a two-year remission,
12% - Strong hormonal ointments (Budesonide, Mometasone, Betamethasone). At first they give a very good therapeutic effect, but then the condition of the patients worsens sharply, you have to apply the ointment more often, and it helps worse. A vicious circle is formed, comparable to drug addiction. Long-term use of such drugs leads to dysfunction of the adrenal cortex and gradual atrophy (necrosis) of the skin,
12% - Baths, steam rooms, saunas and pools are an absolutely harmless, but ineffective method of treating psoriasis. According to most patients, staying in a steam room and then swimming in cool water allows you to calm the itching for a while and provide yourself with a quiet sleep, which in itself is not bad. But there are also people in whom psoriasis, on the contrary, exacerbates from excessive humidity and sudden changes in temperature,
12% - Sports and outdoor activities - any pleasant physical activity, whether cycling, dancing, hiking or playing football, help to improve well-being, strengthen immunity, increase the mood and self-esteem of the patient, which can not but have a beneficial effect on the course of psoriasis ,
12% - Ointments based on calcitriol (Osteotriol) or calcipotriol (Dayvonex) - these drugs saturate the epidermis with the active form of vitamin D, penetrate the blood well and normalize calcium metabolism, and this almost always leads to a decrease and the gradual disappearance of psoriatic plaques. Of the minuses: ointments are expensive, the best are of German manufacture, they are sold mainly on order,
10% - Therapeutic starvation is a radical method of treating psoriasis, which allows achieving remission or at least reducing the area of skin lesions to almost all patients, but has a lot of contraindications. Treatment starvation courses are best taken in a hospital setting, and even more so you can’t start starving without permission, without examination and consultation with a specialist,
10% - Salicylic acid ointments - strictly speaking, do not treat psoriasis at all, but contribute to the healing of plaques and the disappearance of crusts. After the skin is cleansed of the stratum corneum, it is advisable to start treatment with other means, for example, the same solidol. Salicylic ointments in a sense prepare the epidermis, since they improve the absorption of active substances,
10% - Phytotherapy - this term means all methods of treating psoriasis with the help of medicinal plants: ointments, lotions, rubdowns, compresses, taking decoctions and infusions inside. Burdock roots, marsh calf, dandelion, wheatgrass, chicory, lingonberry, chamomile, string, St. John's wort, celandine, nettle, raspberry, birch, oregano, valerian and many other plants demonstrate good efficacy, but herbal medicine is always fraught with allergies and side effects,
9% - Therapeutic baths with turpentine and herbal decoctions are a safer method of treating psoriasis, since the active substances affect the skin for only a short time.If you have no contraindications for taking hot medicinal baths, try taking them every other day for 20 minutes, adding pine gum, freshly ground plantain, decoction of birch buds, juniper leaves or Valerian grass to the water heated to 38 degrees.
8% - Weak and combined hormonal ointments (Hydrocortisone, Fluticasone, etc.) - are often used during seasonal exacerbations of psoriasis, when plaque overgrowth and intolerable itching cannot be stopped by any other method. The treatment of psoriasis with hormonal ointments should be approached very carefully, not to resort to it unnecessarily and to be canceled gradually,
8% - Enterosorbents (Polyphepan, Filtrum STI, Polysorb, Enterosgel) - a good addition to the diet, help cleanse the intestines of debris and normalize, thereby, the blood composition, which will not slow down positively affect the course of psoriasis,
7% - Ultraviolet and quartz irradiation - for some psoriasis patients, regular visits to the most common solarium help, especially in combination with ointments based on active vitamin D. However, quartz lamps are preferable, if only because of the lower risk of developing oncology with regular irradiation,
7% - Vitamin therapy is a very controversial method of treating psoriasis, since in some patients therapeutic doses of vitamins cause a quick improvement in well-being, while in others - the same rapid deterioration with severe allergies and dyspeptic disorders in addition,
4% - dietary supplements are an inexhaustible source of profit for pharmaceutical companies, for which psoriasis with its chronic and purely individual course is just a gold mine. “Revolutionary” psoriasis drugs appear on sale with enviable regularity, however, their composition mainly contains long-known and well-known components. So, before buying a dietary supplement, take an interest in what it consists of: whether it turns out that you have already used it unsuccessfully, or, worse, you have an exacerbation. Keep in mind that the legislation on dietary supplements is very soft, so the true composition of the drug may differ from the information on its label without catastrophic consequences for the manufacturer and seller,
4% - Immunomodulators are serious drugs that can be used for the treatment of psoriasis only according to the testimony of an immunologist and based on immunogram data, otherwise it can only be made worse
4% - Calcium and sodium salts (calcium chloride, sodium gluconate, sodium thiosulfate) - sometimes with the help of a short course of such injections it is possible to stop the exacerbation of psoriasis and reduce the pain of symptoms, however, the introduction of calcium and sodium salts is not considered as an independent treatment method,
4% - Hepatoprotectors (Legalon, Essentiale, Karsil, Liv 52) - stimulate and preserve liver function, thereby indirectly helping it cleanse the blood of toxins and prevent exacerbation of psoriasis. They don’t work without a diet,
4% - Dental care - in some patients, exacerbation of psoriasis occurs due to untreated teeth, when the oral cavity is a constant focus of inflammation and a hotbed of bacteria, whose waste products enter the bloodstream. To help such a patient, sometimes it’s enough to heal caries,
3% - Cleansing the body - this means not only bowel cleansing using hydrocolonotherapy, but also detoxification courses for other organs: liver, lungs, kidneys. All these activities have a beneficial effect on the course of psoriasis,
3% - Anthelmintic therapy - the presence of worms, giardia and other parasites in the body inevitably leads to poisoning by the products of their vital activity, and blood pollution turns into an outbreak of psoriasis. Therefore, it is recommended that all patients with a preventive measure pass feces for analysis,
3% - Plasmophoresis - a technique for hardware purification of blood, which is used in the treatment of severe forms of psoriasis in a hospital. It gives a very good therapeutic effect, but lasts for a short time - for about one and a half to two months,
3% - Cosmetic creams and oils - not bad help to cope with skin peeling, especially when applied immediately after a bath or shower. The simpler and more natural the makeup, the better. Give preference to baby creams based on vegetable oils,
3% - Psychics and healers - it is impossible to objectively evaluate the effectiveness of the magical treatment of psoriasis, however, the patients of the healers and witches claim that they recovered precisely thanks to the sessions and show clean skin. Well, nobody canceled the power of suggestion,
3% Anti-inflammatory drugs for the treatment of psoriatic arthritis - for some patients with ordinary psoriasis, preventive course administration of these drugs helps to avoid exacerbations,
2.5% - Sulfur and zinc-sulfur ointment are the simplest drugs for the treatment of skin parasitic infections (lichen, scabies), but they can also reduce itching and peeling with psoriasis,
2.5% - Purified, thawed, activated, and charged water - there are many methods to give healing water simple properties, starting from consecration in the church and ending with cation-anion separation, but we can only say with confidence that drinking such water will not cause harm to your health, but whether it helps to overcome psoriasis is a big question,
2% - Homeopathy - treatment with microscopic doses of natural poisons in order to trigger an immune response to defeat the disease. With psoriasis, the technique is ineffective,
2% - Heat therapy and infrared irradiation is a controversial method of treating psoriasis, since in some patients warming causes exacerbation instead of improving well-being,
2% - Corticosteroid injections - a “fire” technique, which is resorted to only in a hospital setting and only in the absence of other ways to help the patient with a severe form of psoriasis,
2% - Oat baths are a safe and easy way to reduce inflammation and itching in psoriasis. Regular intake of oat baths to varying degrees helps almost all patients
2% - Cytostatics - highly toxic drugs that damage the kidneys and liver. Used to treat life-threatening forms of psoriasis under strict medical supervision,
1.5% - Apitherapy - treatment with bee products, and more specifically - apitoxin, bee venom. The principle of apitherapy is close to homeopathy - it is expected that the poison will stimulate the patient's immunity. Sometimes it works, but let's not forget that apitoxin is also one of the most powerful natural allergens,
1.5% - Naftalan oil is a unique natural product extracted in the Azerbaijani resort of Naftalan of the same name and used to treat psoriasis by the method of applications and baths,
1.5% - Fungicides - drugs for internal and external treatment of fungal diseases. Sometimes they alleviate the condition of patients with psoriasis, they are used only as directed by a doctor because of the risk of complications,
1% - Yoga, meditation, hypnosis, autotraining, neurolinguistic programming and other personality management techniques can be useful in the treatment of psoriasis, because the success of recovery in any disease depends on the right attitude.
1% - Starch baths are not as effective as oat baths, but they also relieve itching and reduce peeling. Starch can greatly dry the skin, which cannot be said about oatmeal. But some patients need just such an effect. For one procedure, it is necessary to dissolve 800 g of potato starch in a pan with cool water, and then pour the solution into a warm bath,
1% - Retinoids - vitamin A preparations, provide symptomatic treatment of psoriasis, since it is with a deficiency of this vitamin that a person develops a tendency to dry and flaky skin,
0.5% - Acupuncture is an ancient Chinese technique based on the action of thin needles on biologically active points of the human body associated with the corresponding organs. A very controversial and unsafe method: firstly, a highly qualified specialist in acupuncture will be required, and secondly, great luck for acupuncture to work at all,
0.5% - Bioresonance and wave therapy - modern physiotherapeutic methods that are not very well tested in practice, and so far can not boast of great success in the treatment of psoriasis,
0.2% - Respiratory gymnastics, urinotherapy, laser therapy and other controversial methods deserve attention, but are unlikely to guarantee a positive result.
What solidol is used to treat psoriasis?
At the moment, the shelves of auto parts stores are filled mainly with press-solidol of the US-2 brand - this is an inexpensive and convenient lubricant made in synthetic fatty acids in technical use. However, it is not well suited for the treatment of psoriasis, if only because some manufacturers add harmful additives there to improve performance.
For medicinal purposes, it is best to use a medical solidol manufactured specifically for this, but it is almost impossible to purchase it in a pharmacy in its pure form. Pharmacy chains offer a wide range of ready-made ointments for the treatment of psoriasis, but their effectiveness is called into question by patients. According to reviews, the best result can be achieved with ordinary fat solidol without any mineral and herbal additives, that is, solidol in its pure form.
We recommend that you first test ready-made pharmacy ointments, and then, in the absence of visible improvements, begin to sort out the brands of pure technical solidol in search of a suitable option.
The benefits of solidol in the treatment of psoriasis
The method of treating psoriasis with solidol has been used for more than sixty years and is one of the most popular for several reasons:
Does not require large material costs,
Very easy to use,
Rarely causes allergies and side effects.
It neutralizes burning and itching after the first 2-3 procedures,
Quickly reduces peeling of the skin and accelerates epithelization,
Allows you to completely get rid of the visible manifestations of psoriasis in 60-70% of patients,
It gives a long lasting effect.
Other recipes for treating solidol-based psoriasis
Mix in a clean glass jar 250 g of fat solid oil, 2 tablespoons of bee honey, a quarter tube of baby cream, 2 tablespoons of pharmacy sulfuric ointment, protein of one chicken egg, one teaspoon of rose hips and chestnut ash and one tablespoon of crushed celandine leaves . Store the obtained ointment in the refrigerator and apply liberally to the skin psoriasis affected areas twice a day, morning and evening, rinse off after two hours. Expend all ointment in a week, do not store longer!
Pour 4 tablespoons of ground elecampane root with half a glass of boiling water and keep in a water bath for 15 minutes, then strain the broth, cool slightly and pour in a glass half-liter jar of solid oil, mix thoroughly and store the prepared ointment in the refrigerator for no longer than two weeks. Treatment of psoriasis with this ointment is carried out twice a day for one hour, after which the skin is washed with water with baby or tar soap.
Mix 300 g of solid oil, 100 g of linden honey and 2 egg yolks in a glass jar. Store the finished ointment in the refrigerator for no longer than two weeks, and during this time, apply it thinly to psoriatic plaques three times a day and rinse off after 2 hours.Then, take another two-week course of treatment for psoriasis with the same medicinal composition, but with the addition of two tablespoons of celandine dry powder. This ointment needs to be washed off after an hour.
Prepare the ash from the branches of rose hips and oak bark. Mix 25 g of such ash with one hundred grams of solid oil and ten grams of dry celandine powder, close the jar and store it in a dark, cool place for two weeks. Then mix thoroughly and put the finished ointment in storage in the refrigerator. Treatment of psoriasis with this composition is carried out three times a day for 1-1.5 months. Apply the ointment with a thin layer on the plaques and wash off with baby soap after 2 hours.
Recommendations and contraindications for the treatment of psoriasis with solidol
This technique has no direct contraindications, since the components of solidol do not penetrate the blood through the skin and do not cause significant changes in the body. However, both solidol and ointments based on it can cause allergic reactions. Therefore, regardless of whether you are prone to allergies, before starting treatment with a ready-made ointment or a folk remedy of your own preparation, check if solidol is suitable for you.
Be sure to conduct a preliminary skin test for allergies or individual intolerance to solidol. To do this, apply a little substance to the skin of the inner surface of the elbow and hold for 12 hours without rinsing. If redness, itching and swelling do not appear, you can proceed with the treatment of psoriasis with solidol.
The success of therapy largely depends on the lifestyle that the patient adheres to. It is necessary to follow the diet prescribed by the doctor and refrain from drinking alcohol. It is very useful to undergo a course of body cleansing with freshly squeezed vegetable juices or herbal infusions before starting treatment. The less toxins your blood contains, the lower the risk of seasonal exacerbations of psoriasis, and the higher the chances of taking the disease under control. Take care of yourself and be healthy!
Solidol-based psoriasis ointments
On sale you can find many ointments for the treatment of psoriasis, including those based on solidol (by the way, some of the most effective, not including hormones), which one to choose? Everything is very individual, because the composition of the drugs is different, and even the concentration of solidol in them is not the same. Although it is called the main active ingredient, it follows from most instructions that there is a tenth of pure solidol there, and all the rest are additional components of dubious effectiveness.
Ready-made ointments for the treatment of psoriasis based on solidol are divided into three types according to their composition:
Herbal - Kartalin, Markin ointment,
Vegetable and mineral - Magnispor, Makeev’s ointment,
Mineral - Rybakov ointment.
In order to choose the best option for yourself, it is recommended to take one course of treatment with ointments of each group and compare the effect. If there are no improvements, you can resort to the treatment of psoriasis with pure solidol or home-made ointments based on it. We will give detailed recipes below, and begin the conversation with a discussion of the most popular ready-made ointments.
The standard course of treatment for psoriasis with any of the following ointments is 4-8 weeks, it is not worth counting on a lasting positive effect. But after a week, the itching and external manifestations of the disease should decrease, and if this does not happen, then it hardly makes sense to continue using the drug, it is better to try another one. All ointments are applied with a thin layer on the affected areas of the skin 1-2 times a day and are not washed off . Additional aspects of treatment can be found in the instructions for each specific drug.
For comparison, we present the composition of the most popular solidol ointments for psoriasis:
The composition of the preparation contains aqueous extracts of white birch leaves, a series of tripartite celandine, calendula officinalis, calendula marsh, lanolin, camphor, linseed oil, liquid paraffin, and medical solid oil.
Not registered as a medicine.
Medication for psoriasis
In the case when the patient was diagnosed with moderate or severe psoriasis, or when other types of treatment do not help, the doctor may suggest an oral or injection option for taking medications.
The most common oral and injectable drugs used to treat psoriasis include:
This class of drugs affects your immune system, stops the effects of inflammatory processes on the immune system. Such drugs are administered intravenously.
Over the past 15 years, the FDA has approved 11 biological drugs for the treatment of psoriasis:
A newer biological product that acts on the main cytokine, an interleukin-17A inhibitor (IL-17A), has shown impressive therapeutic results.
Ikekizumab was approved in March 2016, and it has shown very promising results in clinical trials. According to the National Psoriasis Foundation, in 1/3 of the subjects, the skin became clear after three months of using the drug. Other recently approved biological products, Brodalumab and Secukinumab, also target an IL-17 interleukin inhibitor.
Doctors prescribe biological preparations for patients with moderate to severe psoriasis. In addition, they are prescribed to those patients who have a lack of response to other types of treatment or because of possible side effects. Biological preparations are not recommended for use by patients with a weak immune system or an organism weakened by any infection. Before you start taking biological drugs, your doctor must conduct a full examination for tuberculosis and the presence of other infectious diseases.
Price? Biological drugs are quite effective in the treatment of psoriasis, but are expensive. According to a 2014 study, adalimumab treatment can cost more than $ 39,000, Etanercept, more than $ 46,000 a year, and ustekinumab, more than $ 53,000 a year.
Retinoids reduce the production of skin cells, however, as soon as you stop taking them, the symptoms of psoriasis are likely to return. Side effects from retinoid treatment are extremely unpleasant: hair loss and inflammation of the mucous membranes of the mouth.
Pregnant women or those planning a pregnancy in the next three years are strictly forbidden to take retinoids due to the high risk of birth defects in the fetus.
Cyclosporin (Sandimmun) suppresses the body's immune system and the manifestations of psoriasis are reduced. However, this means that it is very easy for you to get sick, as the immune system will be weakened. Side effects from the drug are also quite serious: it contributes to an increase in blood pressure and impaired renal function.
Methotrexate, like cyclosporine, suppresses the body's immune system. Taking the drug in a lower dosage has a high probability of reducing side effects, but with prolonged use, it still seriously affects the body. Damage to the liver and a decrease in the production of red and white blood cells are just a small part of the side effects of taking the drug.
No, it’s not at all about using a scalpel to remove non-healing plaques for years, as you might think. A domestic specialist, Dr. V. Martynov, proposed a very interesting, and most importantly, effective, method of surgical treatment of psoriasis. He carries out an operation to restore the small intestine valve, which is responsible for cleansing this section of the intestine from toxins and pathogenic microflora. As a result, after a few months, immunity is restored, and a person forgets about psoriasis for at least several years.
Phototherapy with 311 nm narrow-band ultraviolet radiation
It is this method of ultraviolet radiation that shows the best effectiveness in the treatment of psoriasis. Narrow-band phototherapy is suitable for patients with any type of skin, including those who have very light and sensitive skin.The incidence of side effects is minimal, the procedure takes only a few minutes, and after 10 weeks of regular visits to the physiotherapist, a stable remission usually sets in.
Over the past few years, lamps for holding narrow-band phototherapy sessions have appeared in many public hospitals, so the technique has become more affordable.
Calcitriol Vectical Ointment
More recently, a new American-made ointment based on active vitamin D, calcitriol - Vectical - was on sale. In clinical trials of this drug, 800 volunteers suffering from psoriasis took part. For 18 weeks, they applied ointment daily to the affected areas of the skin, and during this time, a third of the subjects showed significantly reduced disease manifestations.
For children under 18 years of age, Vectical ointment is contraindicated so far, since the necessary tests have not yet been completed. The manufacturer also warns that during treatment it is impossible to stay in the sun for a long time, it is undesirable to combine the use of Vectical ointment with the intake of diuretics, and it is not recommended for people with calcium metabolism disorders.
PUVA therapy is a type of phototherapy. This method of treating psoriasis works using a photoactive substance and the subsequent irradiation of the patient’s skin with type A ultraviolet radiation (waves from 315 to 400 nm in length).
A positive result with PUFA therapy is achieved in more than 80% of cases. The effect is already noticeable after the first 4-6 sessions, and remission can last up to several years.
PUVA therapy slows down the growth of epidermal cells, and this is achieved by exposing the patient to type A ultraviolet radiation after taking photoactive preparations of the psoralen group.
Education: A diploma in the specialty of “General Medicine” and “Therapy” was obtained at the N. I. Pirogov University (2005 and 2006). Further training at the Department of Herbal Medicine at Peoples' Friendship University of Moscow (2008).
Two different treatment approaches
Psoriasis and its treatment can be approached from two sides.
The first approach is more common, its treatment methods are used by doctors.
This is a medical approach. He claims that the causes of psoriasis are not fully understood and understood, so the disease is incurable.
However, scientists have thoroughly investigated the local mechanisms of plaque formation on the skin. By blocking these mechanisms, it is possible to quickly eliminate the external manifestations of the disease, that is, its symptoms: psoriatic plaques, itching and pain. And in modern medicine there are many different ways to eliminate the symptoms of psoriasis.
Gordian psoriasis knot is easier for doctors to cut than untangle ...
This approach looks at the patient as a broken mechanism that cannot be completely repaired, but can be slightly patched up and needs to be periodically lubricated. The emphasis in this approach is on various means for “repairing" the body, for example, medicines. And little depends on the patient himself. They tell the patient what to do, he does it and quickly gets some kind of result. However, unfortunately, more often the result just as quickly disappears. Then you have to try the next treatment method from the list or look for a new adviser.
The main problem of the medical approach is the ignorance of the root causes of psoriasis.
Of course, doctors can quickly eliminate the external manifestations of the disease. But only as long as patients continue to follow medical methods of treatment.
And after their termination after some time, the disease returns again. In addition, medical devices often cause complications.
The second approach is much less common.
This is an evolutionary view of the disease. He claims that the causes of psoriasis are known - these are inappropriate conditions for the existence of a person.
Such reasons are considered: inappropriate climate and lack of sun, low physical activity, chronic stress and others.A special case of the evolutionary approach to treatment is the Pegano method “Natural Way”, in which our diet is called the main cause of the disease.
The essence of the evolutionary approach is as follows:
changing living conditions and even the way of thinking - and so we eliminate the initial causes of the disease. And if there is no reason, then there will be no manifestations. That is, psoriasis is curable!
This approach goes much further than the first and is able to get rid of the disease forever. However, it requires the active participation of the patient and time. A lot depends on the desire and determination to be cured, on patience and perseverance.
Thus, the advantages of the evolutionary approach are the opposite of the disadvantages of the medical one. The evolutionary approach leads to stable remission in the complete absence of side effects. In addition to getting rid of psoriasis, the methods of the evolutionary approach increase the overall health of a person. Although they do not act as fast as medical methods.
The most common form of psoriasis
We consider medical methods of treating the disease using the example of its most frequent form - vulgar psoriasis. This form affects 9 out of 10 of all patients.
Vulgar psoriasis is also called:
- plaque, simple, ordinary, chronic stable.
Outwardly, it is manifested by psoriatic plaques. These are thickened red patches of inflamed skin ranging in size from 0.5 to 30 cm. Usually, plaques peel off and are covered with silver scales. Plaques are single and multiple. In the active phase of the disease, they grow and merge with each other.
Often, plaques are located symmetrically on the skin and primarily occur:
- on the extensor surfaces of the knees and elbows, on the scalp, above the sacrum.
Psoriatic plaques have an unsightly appearance and are clearly visible. Therefore, the appearance of the skin greatly interferes with patients in everyday life and often leads to the desire to hide from other people.
The disease isolates the patient from other people ...
Often patients complain of itching and pain in the area of rashes.
Vulgar psoriasis is of several types:
- scalp psoriasis, inverse, intertriginous (intertrigo - diaper rash) or reverse psoriasis in the area of large skin folds, palmar-plantar non-pulmonary psoriasis, seborrheic psoriasis, psoriasis with nail damage.
There are types of diseases without plaque formation: teardrop and pustular psoriasis. An extensive form of the disease that can affect the entire surface of the skin is called erythroderma.
Plaque psoriasis differs from these forms of the disease: pustular, teardrop and erythroderma. However, different forms can occur in one patient at the same time or turn into one another. But these forms are much less common, so we will consider them in separate articles.
I. Medical approach to the treatment of psoriasis
First, consider the treatment of the disease with medical methods. After all, meeting with the disease for the first time, most of us first turn to doctors for help.
There are many medical treatments for psoriasis. Therefore, when choosing a treatment, the doctor faces several problems.
The first problem: you need to choose the appropriate treatment methods for a particular patient.
In the case of a medical approach, this suggests that the patient will be able to accurately follow the doctor's recommendations. And he will have to do this for a long time, again returning to treatment during exacerbation. After all, doctors consider psoriasis an incurable disease.
The medical treatment of psoriasis resembles an ungrateful Sisyphus labor ...
The second problem: you need to choose the most effective and safe methods.
Effective ones are those that eliminate the external manifestations of psoriasis quickly and preferably for a long time. However, medicine, unfortunately, cannot affect the duration of remission, and it itself recognizes it. Safe are those that do not cause side effects. However, complete safety due to prolonged treatment is not possible.
The third problem: very little time is allocated for the reception of one patient.
During the admission, the doctor must accurately assess the patient's condition and take into account all the features of his case. This will help to choose the best treatment for him - effective and safe. And the doctor must do all this quickly. If this is not done, the patient will inevitably suffer. It will either be difficult for him to follow the treatment regimen, or he will be dissatisfied with the result of treatment and the duration of the effect, or he will face various complications of therapy. And, most likely, all this will manifest itself together.
Unfortunately, this is usually the case with psoriasis. Especially with severe forms of the disease affecting a significant surface of the skin.
So, according to an American study,
78% of patients with severe skin lesions consider the treatment not effective enough and do not make the disease more manageable.
The reason for this is 59% of patients said the lack of support and interaction from the doctor.
With mild psoriasis, when no more than 5% of the skin surface is affected, the disease does not significantly affect the patient’s physical health. However, at the same time, its negative impact on the psychological and emotional state of the patient can be huge.
The ideal doctor and patient - who are they?
The ideal doctor does not treat the disease, but the patient. This means that behind the manifestations of the disease, the doctor sees the person himself, and not just the physical condition of the body. In this case, the specialist does not focus on treatment regimens or indicators of psoriasis activity - BSA or PASI. After all, each patient is unique: of different sex and age, each has its own family and circle of friends, its own psychological and emotional states. Patients have different opinions about the desired treatment results. As well as what to consider the most effective and acceptable method of treatment.
Therefore, the doctor should choose a method based on the needs of a particular patient.
First of all, the ideal doctor should assess the degree of suffering of the patient: not only physical - itching and pain - but even more psychological.
And also take into account the patient’s lifestyle, his personal preferences, gender, age, bad habits, level of affluence.
For a doctor, the psychological state of a patient with psoriasis should be more important than anything else ...
And only secondarily does the doctor look at the objective indicators of the disease. Where are psoriatic plaques located and how thick. How intense is peeling and redness of the skin. What treatment methods have been used and with what result.
It is important for the patient himself to be realistic with regard to the medical approach:
the patient needs to clearly understand what goals are achievable. The realistic goal of a medical approach will be, for example, getting rid of itching, pain and the most noticeable plaques for a while.
After all, medicine cannot completely and completely eliminate psoriasis; the doctors themselves openly admit it. Also, medical methods of treatment require active, accurate and long-term use. But such a regime is difficult to maintain for a long time.
Some patients do not want to spend time and effort on skin care at all and agree only on minimal treatment. Others cannot endure even the smallest manifestations of psoriasis. Still others, aware of the limitations of the medical approach, will turn to alternative methods.
Keeping all this in mind, let's look at what methods the doctor has for eliminating the symptoms of psoriasis: when and how they are used, their advantages and disadvantages.
1. External means
We begin to consider medical treatments with external agents. They are also called local remedies.
External agents act directly on the skin. And in the treatment of psoriasis, doctors use these drugs in the first place.
Doctors believe that in 80% of cases of a mild to moderate disease, external agents are sufficient to control its symptoms, and the frequency of side effects is acceptable.
Outdoor tools like new graffiti on top old…
Essential medicines for local use:
- corticosteroids (hormones), vitamin D analogs, vitamin A analogues (retinoids), calcineurin inhibitors, tar, anthralin, salicylic acid.
Also external treatment methods include:
- phototherapy, photochemotherapy (PUVA), climatotherapy.
Why is the choice of the external dosage form important?
Medicines for the local treatment of psoriasis are available in different dosage forms:
- ointment, cream, gel, lotion, spray, foam, shampoo and others.
The form of the external drug greatly affects its ability to penetrate the skin, and therefore the effectiveness of the treatment.
So, for example, ointment penetrates the skin better than cream.
Different dosage forms are suitable for different parts of the body. For example, external agents for the treatment of psoriasis of the scalp are produced in the form of shampoo, spray, gel, etc. And on the skin of the trunk and extremities it is more effective to use ointments.
The preferences of the patient himself when choosing a dosage form are also important. It is more convenient for someone to use a less oily and, most importantly, less noticeable cream during the day, but a more oily and effective ointment at night. But for some, these restrictions are not so important. Because, for example, their profession is not associated with constant contact with people.
Modes of use of external drugs
In the treatment of psoriasis, there are different modes of using external agents.
As we said above, in the arsenal of doctors there are no ways to achieve constant remission. Therefore, medical means have to be used for a long time. However, the problem is that
prolonged use causes an addictive effect. That is, the product over time ceases to improve the condition of the skin.
Also, various and rather strong side effects begin to occur. Then the funds that have ceased to help are exchanged for others, often more powerful ones.
Medical treatment of psoriasis is like running with obstacles (complications) in a circle (from remission to remission)
External means are used both continuously and intermittently.
The general rule is this: agents with high activity are used continuously, but not for long - only until the desired skin condition is achieved. And then they switch to the maintenance mode, intermittently. This reduces the risk of reducing the effectiveness of the drug over time, and also reduces the risk of complications.
If a long-term continuous use of external agents is prescribed, then they begin with less active, but able to eliminate the symptoms. Or choose a tool that rarely causes adverse effects with prolonged use.
In any case, constant monitoring by the doctor is required, regardless of the treatment regimen for psoriasis.
What to do if one external remedy is not enough
An external remedy alone is not enough to completely eliminate the symptoms. Or the skin condition may noticeably improve, but some persistent psoriatic plaques may still remain. In this case, several external agents are used at once.
In this case, the means must be compatible with each other.
If you need to use incompatible products, they are used at different times during the day.
Treat psoriasis with medical means how to assemble a puzzle: you need to consider a lot of things ...
For example, hormonal drugs can be used simultaneously with an analogue of vitamin D. But in combination with phototherapy, an analogue of vitamin D is used only after an irradiation session, since ultraviolet light destroys the drug.
Possible problems of external funds
In the treatment of psoriasis by external means, it is necessary to follow the treatment regimen for a long time and clearly. This often becomes a problem for several reasons:
- the product is poorly tolerated, the result does not meet expectations, the patient is afraid of side effects, there are no various convenient dosage forms, too much skin area is affected, the elderly patient is not taken into account, the price of treatment is too high.
We emphasize once again that all this is important to consider when choosing a method and means of treatment.
Now we will consider specific forms of external funds and begin with their main form - hormonal drugs.
1) External hormones - corticosteroids
For over half a century, external corticosteroids have remained in medicine as the main drug for the treatment of psoriasis.
They are especially treated with forms that affect no more than 10% of the skin (for reference: the surface of the palm without fingers is equal to 0.5% of the skin).
Also, these drugs are called glucocorticoids, glucocorticosteroids, steroid hormones, external hormones.
Mechanism of action. The main actions of hormones: they inhibit inflammation, reduce the rate of division of keratinocytes and inhibit local immunity.
Hormones are like a road roller: everything suppresses and depresses ...
Efficiency. In Russia, the European classification of hormonal drugs is used. In it, corticosteroids are divided according to activity into 4 classes: 1 class - weak, 2 class - medium, 3 class - strong, 4 class - very strong.
Consider what classes different drugs belong to:
- Weak (class I):
- Hydrocortisone acetate 1% Hydrocortisone 1–2.5% Prednisolone 0.5%
- Alclomethasone dipropionate 0.05% Clobetasone butyrate 0.05% Flumetasone pivalate 0.02%
- Betamethasone valerate 0.1% Betamethasone dipropionate 0.05% Fluocinolone acetonide 0.025% Methylprednisolone aceponate 0.1% Triamcinolone acetonide 0.1% Hydrocortisone butyrate 0.1% Mometazone furoate 0.1% Fluticasone propionate 0.05%
- Clobetasol Propionate 0.05%
The effectiveness of an external hormonal agent also depends on its dosage form. For example, ointment penetrates the skin best, but it is not always applicable. The cream penetrates the skin worse than the ointment, and the lotion is even worse.
Also, the permeability of the skin itself affects the effectiveness of hormones. It is important to consider when choosing a class of hormone and dosage form. The highest permeability of the skin is on the face and eyelids, the average on the body, the lowest on the palms and soles. The higher the permeability of the skin, the hormonal product should be weaker.
Very strong corticosteroids significantly improve the condition of the skin 2 weeks after the start of use. But it is important not to use them longer than 4 weeks. The period of use of weak hormones is not precisely defined.
Application scheme. The usual pattern of hormone use is as follows. A very strong or strong hormonal agent is applied to the affected skin daily 2 times a day. After achieving the desired result, usually after 2-4 weeks, the frequency of use is gradually reduced to 1 time per day 2 times a week. The onset of remission of psoriasis is supported by non-hormonal moisturizing and emollient cosmetics.
If the effect of hormones is insufficient, they are combined, for example, with salicylic acid, phototherapy or cyclosporine.
Side effects. However, it is important to keep in mind that the use of hormonal medications in the treatment of psoriasis often leads to local (skin) and general (due to absorption in the blood) side effects.
Long-term use of external corticosteroids, especially the most powerful of them, can lead, for example, to such local complications:
- atrophy of the skin - a change in the normal structure and thinning of the skin due to the vasoconstrictive effect of hormones, stretch marks - stretch marks, skin stretch bands, purple - multiple hemorrhages in the skin, perioral dermatitis - inflammation of the skin around the mouth, steroid acne - acne, contact dermatitis - inflammation of the skin at the place of application of hormonal agents, hypertrichosis - excessive hair growth, folliculitis - inflammation of the hair follicles, hypopigmentation - weakening of the normal color of the skin, telangiectasias - persistent expansion of small vessels of the skin and others.
A rebound phenomenon may also occur: after the abrupt cancellation of hormones, psoriasis returns quickly and with renewed vigor.
In addition, in real life, hormones are often used without the supervision of a doctor and have been used for too long. Therefore, after discontinuation of treatment, the disease soon returns again and even progresses.
Given the risk of complications, corticosteroids can hardly be called the optimal treatment for psoriasis.
2) Vitamin D analogues
Calcipotriol is a synthetic analogue of vitamin D.
Mechanism of action. Analogues of vitamin D inhibit the division of skin cells (keratinocytes) and inhibit immune inflammation in psoriasis.
Efficiency. Calcipotriol treatment is quite effective.
Compared to a strong corticosteroid in the form of an ointment, calcipotriol was even slightly more effective, second only to the strongest class 4 hormones.
Application scheme. Calcipotriol ointment is applied to the plaques once a day. And the total duration of the course should not exceed 2 months.
Combinations of vitamin D analogues with hormonal drugs are also used. However, although hormones eliminate skin irritation, and the overall effectiveness of treatment increases, the side effects of corticosteroids, unfortunately, remain.
Calcipotriol is also used together with ultraviolet, PUVA or systemic drugs. This allows you to reduce the radiation dose during phototherapy and the dose, and therefore, the toxicity of systemic drugs, for example, cyclosporine or methotrexate.
Side effects. It is important to note that patients tolerate vitamin D analogues better than hormonal drugs. Among the most common complications of calcipotriol treatment are local skin irritation, itching, and burning. In this case, the usual dose of calcipotriol rarely leads to an increase in the level of calcium in the blood (hypercalcemia) - another possible side effect.
3) Vitamin A analogues - retinoids
Retinoids are synthetic analogues of vitamin A for the treatment of psoriasis. They can be used both externally and internally. Tazarotene belongs to external retinoids, but in Russia it is not officially sold.
Other external retinoids, for example, retinoid ointment (with isotretinoin), are sold here, but they were not effective for psoriasis.
Mechanism of action. Tazarotene reduces the rate of division of skin cells (keratinocytes) and has an anti-inflammatory effect.
Efficiency. In studies, tazarotene was about the same as hormones, but it led to longer remission after treatment.
Application scheme. Tazarotene is produced abroad in the form of a gel and cream in concentrations of 0.05 and 0.1%. They are applied to the skin 1 time a day before bedtime. The course of treatment is from 6 to 12 weeks.
Side effects. The main complication of tazarotene treatment is skin irritation in and around psoriatic plaques. However, usually such irritation does not lead to the refusal of treatment with this retinoid.
4) Calcineurin Inhibitors
External calcineurin inhibitors - tacrolimus and pimecrolimus - are used for atopic dermatitis. They are not officially registered for the treatment of psoriasis.
Mechanism of action. Calcineurin inhibitors have an anti-inflammatory effect, blocking the activation of immune cells (T-lymphocytes) in the area of inflammation.
Calcineurin inhibitors block a specific immune cell activating enzyme
Efficiency. Calcineurin inhibitors were especially effective for reverse psoriasis (intertriginous form), psoriasis of the face and genitals. Improving the condition of the skin usually occurs during the first week.
On the trunk and extremities, these drugs do not penetrate the skin well through thick psoriatic plaques, so they are applied under a film (occlusive dressing) or together with salicylic acid.
Application scheme. Calcineurin inhibitors are applied to the affected skin twice a day until plaques disappear. These drugs are also used to prevent exacerbations as maintenance therapy.In this case, they are applied to the skin less often, but for a long time.
Side effects. Calcineurin inhibitors do not cause skin atrophy and other side effects that occur during treatment with hormonal agents.
The most common side effects of calcineurin inhibitors are irritation, itching, and burning at the site of application. However, they disappear a few days after the start of treatment. They can also be loosened by cooling the ointment before application and using moisturizers afterwards.
Tar has been used in the treatment of skin diseases for more than two thousand years. Everywhere in the treatment of psoriasis, coal tar preparations are used, in Russia, birch is mainly available.
Mechanism of action. It is not known exactly, but it is believed that tar suppresses the division of keratinocytes. Tar also constricts blood vessels and has a disinfecting effect.
Efficiency. Compared to strong class 3 corticosteroids, tar was much less effective. But it is effective in about the same way as vitamin D analogues, which, however, act faster.
Application scheme. In 1925, an American dermatologist, William Haeckerman, described a very effective treatment for psoriasis. He used coal tar in combination with ultraviolet.
Many dermatologists consider the Haeckerman method the gold standard in the treatment of psoriasis: highly effective and giving long-term remission.
Tar is often used in the form of ointments, including together with salicylic acid. Shampoos, soaps, creams, lotions, alcohol solutions and foams are also produced with tar.
Side effects. The main disadvantages of tar: it smells bad and also stains skin, hair and clothes. Tar can also provoke inflammation of the skin and hair follicles, burning sensation at the site of application.
It was believed that tar potentially provokes malignant tumors, but scientists have not confirmed this.
Tar is not used in the treatment of teardrop and pustular forms of psoriasis, as well as erythroderma, as it can cause their exacerbation.
Anthralin was first obtained from the bark of a South American tree. In the treatment of psoriasis, it has been used since the beginning of the last century.
Anthralin has not been sold in Russia since the late 90s.
Mechanism of action. It is believed that anthralin normalizes the maturation of keratinocytes and suppresses the activity of immune cells in the area of skin inflammation.
Efficiency. Compared to vitamin D analogues, anthralin has been shown to be less effective.
In another study of anthralin in 2120 patients, 95% of them got rid of the manifestations of psoriasis in just 15 days.
Application scheme. Anthralin ointment is applied to plaques in two ways: for 24 hours or for 15-30 minutes. With good tolerance in each of the schemes, the concentration of the ointment is gradually increased. It usually takes 3-4 weeks to cleanse the skin.
Side effects. The use of anthralin is associated with two problems.
Firstly, Anthralin stains everything in red-brown color: skin, nails, clothes, bedding, plumbing. You have to apply it under dressings and wear clothes, which then will not be a pity to throw away.
Anthralin colors everything in red-brown
Secondly, anthralin causes severe inflammation of the skin around the plaques: up to blisters and ulcers. Burning sometimes becomes so strong that treatment has to be stopped. Therefore, anthralin is not used in the fold zone, on the face and genitals, but only on the skin of the trunk and limbs.
Like tar, anthralin is not used for teardrop, pustular psoriasis and erythroderma. Antralin does not provoke malignant tumors.
7) Salicylic acid
Salicylic acid has been used for many years as an external treatment for psoriasis.
Mechanism of action. It is believed that salicylic acid destroys the bonds between keratinocytes and lowers the pH of the stratum corneum. This makes the psoriatic plaque softer and eliminates peeling.
Application scheme.Salicylic acid is applied to the affected skin as an ointment. Often salicylic acid is used with other external treatments for psoriasis. For example, with corticosteroids, calcineurin inhibitors or tar.
Side effects. Salicylic acid can cause irritation, so it should not be applied to healthy skin, as well as mucous membranes, genitals, and around the eyes.
Salicylic acid is not acetylsalicylic acid (not aspirin), salicylic acid must not be taken orally!
Drugs with salicylic acid should not be applied to the skin when taking other salicylates orally, for example, aspirin.
Salicylic acid cannot be applied to more than 20% of the skin surface. All this can lead to poisoning.
8) Ultraviolet: phototherapy, excimer laser and photochemotherapy (PUVA)
Ultraviolet has been used in the treatment of psoriasis for more than a hundred years.
Ultraviolet is of three types: A, B and C. In the treatment of psoriasis, only two types are used: A and B.
Mechanism of action. It is believed that ultraviolet light reduces the rate of skin cell division, the activity of T-lymphocytes and the production of substances that stimulate inflammation.
Phototherapy is called an independent, that is, without additional funds, the use of ultraviolet radiation in the treatment of psoriasis.
Efficiency. Significant improvement in the condition of the skin takes about two months, but the remission is quite long.
Application scheme. Typically, radiation sessions are carried out three times a week. Session time is selected depending on the type of skin.
Phototherapy is used in the treatment of teardrop-shaped psoriasis, but not in pustular forms and not in erythroderma. It is also not applicable for psoriasis of the scalp and reverse psoriasis: ultraviolet simply does not reach these areas of the skin. True, there are special UV combs to treat psoriasis of the scalp.
A significant advantage of phototherapy is that there is no need for other external means: creams, ointments, and others.
However, ultraviolet light is often supplemented with external drugs: tar, anthralin, and analogues of vitamin D. On the one hand, this increases the effectiveness of treatment, and on the other, it reduces the number of radiation sessions.
A solarium for phototherapy with special treatment lamps can be assembled independently and treated at home.
Side effects. To procedures with ultraviolet need to be careful. Prolonged uncontrolled exposure may cause skin burns. A constant “burning" can even lead to skin cancer or melanoma.
An excimer laser appeared in the late 90s to treat persistent limited psoriatic plaques. It allows you to irradiate ultraviolet skin areas 1-3 cm in size. The surrounding skin does not suffer.
Excimer laser can be used for intertriginous psoriasis, scalp psoriasis and palmar-plantar form of psoriasis.
PUVA (or PUVA) is an abbreviation made up of the letters in the name of a psoriasis treatment method: Psoralen and Ultraviolet A.
Psoralen is a chemical substance that, when taken orally in combination with ultraviolet A irradiation, leads to the disappearance of psoriatic plaques.
Psoralen can be applied directly to the skin or added to bath water.
Psoralen can be used externally - add to the bath before a phototherapy session
The restrictions on the use of PUVA are the same as with general phototherapy.
PUVA is faster than conventional phototherapy. But it can cause nausea, as well as itching and pain in irradiated skin. PUVA can also provoke early skin aging: spots, thinning, wrinkles, and dryness.
It has been proven that frequent use of PUVA increases the risk of developing skin cancer.
Heliotherapy or sun therapy - this option of climatotherapy in the treatment of psoriasis is widely used. After all, vacation under the sun on the seashore has a good effect on the condition of the skin and on the mood of the sick.
The Dead Sea is especially famous in this regard. Natural conditions there are such that ultraviolet B practically does not reach the earth's surface, which means that the risk of skin burns is minimal. Usually, the disappearance of psoriatic plaques takes about a month.
The Dead Sea is in fact salt Lake
Of course, other places under the sun are no less effective, and plaques disappear in the same 4 weeks. The main thing in the first few days to remember about the danger of sunburn.
The disadvantages of such therapy are the price and time: not everyone can afford to go to the sea for a month.
2. System tools
Systemic drugs for the treatment of psoriasis are drugs that enter the body, for example, in the form of tablets or with injections. That is, they act from within, not externally.
Systemic drugs are used only for severe forms of the disease or if external agents do not give a result. All of these medications can cause very serious side effects.
The main systemic drugs are methotrexate, cyclosporin and acitretin. Further we will consider each of them in more detail.
Persistent psoriasis may require continued use of systemic medications. Indeed, for doctors it is an incurable disease. To avoid severe complications, systemic remedies alternate. For example, methotrexate and cyclosporin are changed every 6 months.
Acitretin is an analogue of vitamin A, they are also called retinoids.
Acitretin eliminates manifestations of persistent psoriasis if external remedies and phototherapy have not helped.
Mechanism of action. Acitretin normalizes the division and maturation of skin cells - keratinocytes.
Efficiency. In different patients, the effectiveness of acitretin is different. The medicine is less effective than methotrexate and cyclosporine. A significant improvement in skin condition takes 3-4 months.
Application scheme. Acitretin is taken orally in capsule form once daily with meals.
Side effects. The most dangerous side effect of acitretin is the ability to disrupt embryo development.
Acitretin is completely eliminated from the body for a very long time - within two years. Therefore, it is desirable that women of childbearing age not be treated at all.
Acitretin causes severe damage to the embryo. Women should not plan a pregnancy earlier than 3 years after treatment with acitretin.
Often, shortly after the initiation of acitretin treatment, patients develop dryness and peeling of the lips, cracks in the corners of the mouth with the addition of infection, nosebleeds. The skin, especially on the face, may turn red and peel. Hair on the head may thin out and fall out. All these adverse effects disappear after the end of treatment.
Long-term side effects of acitretin can be manifested by an increase in triglycerides, cholesterol and liver enzymes in the blood. The drug also increases the concentration of calcium in the blood, which can be deposited in the soft tissues of the body and around the joints.
Acitretin cannot be used in patients with impaired liver function, an abnormally high level of blood lipids, and ideally in all women of childbearing age.
3. Biological agents
Biological agents for the treatment of psoriasis are a type of systemic agent. They began to appear in the last 30 years as a result of studies of the immune nature of psoriasis. This is the cutting edge of medicine as a science.
- 1st generation: etanercept, infliximab, adalimumab, 2nd generation: ustekinumab, secukinumab, ixekizumab and others.
Mechanism of action. At their core, biological agents are protein molecules that selectively block specific mechanisms of immune inflammation in psoriasis.
Biological agents are very effective in getting rid of the manifestations of psoriasis.
For them, even PASI100, that is, the ability to remove symptoms by 100%, is no longer unusual.
Application scheme. Biological agents are usually injected subcutaneously with a syringe.
Side effects.The narrow focus of biological agents theoretically ensures the absence of serious complications. In addition, they are more convenient to use than the systemic tools that we talked about above: methotrexate and the rest.
The most common side effects are a cold, upper respiratory tract infection, and weakness.
Before starting treatment, it is necessary to make sure that the patient does not suffer latent tuberculosis, viral hepatitis and does not have a malignant tumor.
This is important because agents that interfere with the immune system reduce the body's defense against infections and malignant degeneration of its own cells.
Before starting treatment with biological agents, it is important to ensure that there are no "sleeping" infections, such as tuberculosis. In the photo: the causative agent of tuberculosis.
Biological agents are not yet widely used because of the very high cost and lack of long-term data on their effectiveness and safety.
How long does remission last after medical treatment?
Remission means that the manifestations of psoriasis have significantly weakened or completely disappeared.
Surprisingly, scientists do not pay much attention to the duration of remission as a result of treatment with medical methods. For the patient, remission is the most important result of treatment.
The duration of remission is difficult to evaluate and compare. After all, it depends on many factors: what different scientists consider as remission, how they conduct research, whether there are any peculiarities in the patients themselves, for example, how and with what they were treated before.
In addition, after the end of treatment, patients are observed only for a limited time, not always sufficient to assess the duration of remission in all.
Supportive therapy also affects the duration of symptoms. For example, patients may continue to be treated, but use doses lower or less likely to apply the product to the skin than during the main course.
Doctors cannot predict the duration of remission
According to scientific studies, different methods of treating psoriasis lead to different durations of remission:
- Corticosteroids. After discontinuation of treatment, the disease usually returns after 1-3 months. And the use of hormones along with other means leads to a reduction in remission time. Analogues of Vitamin D (calcipotriol). The duration of remission is up to 1-2 months. External analogues of vitamin A are retinoids (tazarotene). Remission lasts longer than after corticosteroids. So, for example, 3 months after treatment with 0.1% tazarotene ointment, psoriasis returned in 18% of patients and in 55% of patients who were treated with hormones. Calcineurin Inhibitors. After the main course of treatment, calcineurin inhibitors often continue to be used in long-term maintenance therapy. It may therefore be difficult to find data on the duration of remission after discontinuation of treatment. But the mechanism of action of these funds is unlikely to provide remission for longer than several months. Tar in combination with phototherapy in a hospital (Heckermann's method) led to remission from 8 months to a year or more. But in the treatment they used raw coal tar, which is too dirty to use at home. In Russia, only birch tar can be easily found. According to various sources, phototherapy with ultraviolet B leads to a remission of about 9 months. PUVA therapy is more effective and after it remission lasts from 3 to 16 months. Climatotherapy leads to remission on average from 2 to 6 months. After treatment with methotrexate, in about half of patients, psoriasis returns in the first 6 months. Biological agents lead to remission from 3 to 8 months after cessation of treatment.
In general, it is not necessary to wait for a remission longer than six months as a result of medical treatment.
Of course, medicines can relieve symptoms relatively quickly. But they bring only temporary relief, which is also accompanied by various complications.After all, they act on local mechanisms of inflammation in psoriasis. However, the root causes of the doctors are not known and therefore remain without attention.
The underlying causes of psoriasis are evidenced by the evolutionary approach, to which we proceed.
II. An evolutionary approach to the treatment of psoriasis
The evolutionary approach considers the main cause of the disease a person to be relocated to living conditions that are inappropriate for him as a biological species.
In brief about the evolutionary approach, the following is important:
- About 60 thousand years ago, a man, who came from East Africa, settled around the globe. Life in these territories was significantly different from usual. A person had to adapt to these conditions: for example, climate, food, various types of stress, etc. The body of about 5% of people was less adapted and resistant to adverse factors. Their influence led to the development of psoriasis. The complete or at least partial elimination of these factors will prevent or weaken their negative result - psoriasis.
Next, we will focus on psoriasis and its treatment, based on an evolutionary approach: diet, enough sun, physical activity, sleep and stress.
Although our digestive system has not changed since the migration from Africa, our diet has changed beyond recognition.
We practically stopped eating plants: fruits, vegetables and leafy greens. It is difficult to say what our food now consists of ... Because of this, together with the liver and kidneys, the skin has become an excretory organ that works with overload.
At the same time, medicine pays little attention to nutrition as the cause of psoriasis. Therefore, in scientific articles you will not find methods of treating psoriasis based on a change in nutrition.
However, it is believed that
diet is one of the most important ways to defeat psoriasis.
For example, John Pegano in his method of treatment focuses on diet. There are other nutritional approaches for psoriasis patients. Moreover, they bring benefits not only to the skin, but also to the health of the whole organism.
2. The sun and climate
Man comes from East Africa and is evolutionarily adapted to a high level of solar activity. We practically do not see the sun. For example, on average in a year in Moscow - only 60 sunny days! How many of them did you spend outdoors with bare skin? Not only is the level of solar radiation in our latitudes completely inadequate, but we also specifically hide from the sun.
While under the sun, the skin of a psoriasis patient becomes healthy.
In that case, of course, if it is not photosensitive psoriasis.
You can return the sun to your life in several ways, although each of the options has its own difficulties. Therefore, try to choose the ones that are easiest to translate into your conditions:
- Move closer to the equator, but this, unfortunately, few can afford. Sometimes you can go out to the “warm countries” under the sun, but this is expensive, it happens rarely and this is not enough for a whole year. Take a phototherapy course at the hospital, but not everyone has the opportunity. To create the sun yourself: to collect on your own the source of therapeutic ultraviolet - a solarium with special medical ultraviolet lamps, however it is quite expensive.
Remember that a conventional solarium with tanning lamps is not suitable for treatment!
Although it improves the skin condition in psoriasis, it is not as effective as medical lamps. In addition, ultraviolet light from a conventional tanning bed provokes early aging of the skin and increases the risk of developing its neoplasms.
Conclusion: in one way or another, return the sun to your life, be in the sun whenever possible.
However, remember: excess sun can be poison! Therefore, do not be distracted during sunbathing, for example, to talk, and do not fall asleep. Otherwise, skip the time when it is time to leave the sun, and burn.
3. Physical activity
Man is evolutionarily adapted and needs high physical activity. And today it is clearly lacking for us.
Even doctors say that physical inactivity - reduced physical activity - is the cause of many diseases.
What should be the optimal physical activity? It should help us adapt to physical activity and at the same time guide the body towards a state of health. For simplicity, we mean health for the absence of disease.
Comparing various sports or physical activities with this definition, it is easy to understand that, for example, long-distance running or cycling are not optimal types of physical activity. According to one study, more than half of people regularly running are injured each year. Another study reported 79% of injured runners. We are talking about registered injuries, and not about those that are often not even paid attention to.
According to another study, in 2009 there were approximately 544,000 bicycle injuries in the United States. Also in the United States, due to bicycle injuries, about 300,000 children seek emergency care annually, of which 15,000 cases require hospitalization. In about a third of hospitalizations, head injury is the cause.
The best physical activity for every day that suits us evolutionarily is walking.
Walk more: park further from work and walk. If you can walk and get somewhere in a reasonable time - choose walking!
Walking is the best exercise to which a person is adapted.
In addition to walking, start working with your own body weight several times a week: pull up, squat, push up from the floor. It is not as difficult and tiring as you might think! Start, and the result will pleasantly surprise you!
And remember: a lot is not necessarily good! In addition to injuries, prolonged and unnatural physical activity simply wears out the body and reduces its resource.
4. Drinking water
Water is a universal solvent. It is needed to remove metabolic products from the body, including toxins.
There should be no impurities in ideal drinking water.
To get clean water, buy a reverse osmosis filter. The membrane of such a filter allows only oxygen and water to pass through.
The disadvantage of this method of cleaning: for every liter of clean water, three liters of dirty water are formed, which merge into the sewer. Some of this "dirty" water is collected and used where perfectly clean water is not needed. Also, filters have to be changed periodically.
Of course, you can buy bottled water purified by reverse osmosis. True, the cost of such water is much higher than that of water from its own filter. In addition, you cannot control the quality of purchased water.
It should also be added that the jug type filters do not provide the desired quality of water purification.
Sleep is very important for the normal functioning of consciousness, metabolism, including hormonal metabolism, immunity. During sleep, our nervous energy is restored, which is necessary for an active life during the day.
In patients with psoriasis, sleep disorders are common and are usually manifested by insomnia, apnea (respiratory arrest) in sleep, and restless legs syndrome. And their insomnia is often associated with depression or itching.
To make sleep as effective as possible, it would be nice to follow a few rules.
Ideally, these rules should become habits:
- Go to bed at the same time on weekdays and weekends. Turn off all gadgets and the TV 30 minutes before bedtime: the blue spectrum of their radiation disrupts the production of melatonin. This hormone is very important for a healthy sleep. Your bedroom should be as dark as possible during sleep. Any extraneous light disrupts the normal sleep cycle. Do not eat later than 3-4 hours before going to bed.Digestion consumes quite a lot of energy, which the body during sleep should spend on recovery. Do not physically load yourself after 6 pm. Otherwise, a high level of the hormone cortisol will prevent you from falling asleep. Get a smart alarm clock - sunrise simulator. He will wake you up to the optimal phase of sleep for awakening. Try to do without sleeping pills. Although they help to fall asleep, they also disrupt the structure of sleep, reducing its slow phase, during which the body is restored.
Psoriasis, its features, causes and symptoms
Until now, no scientist can confidently answer the question of why this disease appears. There are several theories, but none of them can explain all the features of the appearance of pathology. The most popular is the hypothesis according to which autoimmune processes play a large role in the development of psoriasis.
Also, the mechanism of the development of the disease is not entirely clear. However, one fact is certain - with psoriasis, the structural and functional properties of the upper layer of skin cells (epidermis) are violated. Usually cells of this layer are updated after a month. However, with psoriasis for reasons not entirely understood, this process is accelerated several times. Cells do not take root on the surface of the skin, and as a result, psoriatic plaques typical of the disease arise. They can be located on various parts of the body. At the same time, they not only spoil the appearance of a person, but also make themselves felt with a severe itch.
A type of psoriasis accompanied by the appearance of plaques is the most common form of the disease. In addition to plaque psoriasis, also called vulgar, there are several types of the disease:
- teardrop shaped
- psoriatic erythroderma.
In some cases, the disease can affect the nails and even the joints. However, methods for treating various types of psoriasis are very similar.
The disease is found in people most often at a young age. The proportion of those who experience psoriasis in childhood or in old age is small.
Even if qualified treatment is carried out, it still does not apply to fast processes. Sometimes the disease can take a protracted course. Sometimes relief comes and the symptoms go away. It seems that the patient has recovered. But actually it is not. There is simply a remission - a period when the disease recedes. But remission is most often interrupted by another exacerbation.
Medical science does not yet know the methods that help patients to completely get rid of the disease. Therefore, the goal of treatment is to alleviate unpleasant symptoms, lengthen periods of remission and prevent complications - diseases of the nails and joints, generalized skin pathology.
Most patients with the first symptoms go to the doctor, believing that traditional medicine knows well how to treat psoriasis. A specialist examines the patient, and if the diagnosis is confirmed, then prescribes treatment.
However, to cure the disease is more difficult than it might seem to the patient at the very beginning of the disease. Fast relief in most cases does not occur. Time passes, and unpleasant symptoms do not pass, and a person can not get rid of the disease. This situation does not suit many. Therefore, many patients turn their attention to alternative methods of treatment, including the methods of traditional medicine, use herbal preparations, and not ready-made medicines purchased at the pharmacy. And some patients use non-traditional methods of treatment due to the fact that traditional medicines and ointments are considered too expensive.
This is not to say that all methods of traditional medicine in the treatment of psoriasis are ineffective. After all, the disease did not appear yesterday. She has been known for a very long time. Therefore, healers from the people have developed reliable ways to combat skin inflammation.Some of these methods have been recognized by modern science.
Therefore, it will not be entirely correct to divide the methods of treatment into traditional and non-traditional. Each case of psoriasis is individual, and many patients are able to help out funds that do not have any positive effect on others.
What are the goals of antipsoriatic therapy? It:
- reduction of unpleasant itching,
- acceleration of the regeneration of superficial skin tissues,
- cleansing the skin of plaques and other rashes,
- normalization of the immune system,
- body detoxification
- normalization of the state of the nervous system.
However, quick healing still does not have to wait - the fight against the disease often drags on for months, years, or even decades.
Before moving on to a review of home remedies, and traditional medicine, we list the treatment methods offered by doctors.
First of all, these are external preparations - ointments, creams, lotions. They have a variety of therapeutic effects:
Keratolytic ointments are especially in demand in psoriasis. After all, their keratolytics contribute to the accelerated exfoliation of the epidermal tissues. The main kertatolytic substance used in psoriasis is salicylic acid. It also has a pronounced anti-inflammatory effect.
In ointments from psoriasis, you can also find:
- zinc oxide
- zinc pyrithione,
- naphthalan oil,
Most ointments are applied to the affected areas of the body with a thin layer. You can not spread several ointments on a sore spot at once - this can lead to unpredictable consequences.
Nevertheless, no matter how good keratolytic and other ointments are, in the treatment of psoriasis, most likely, you can not do without hormone-based ointments. Such ointments are usually prescribed for an exacerbation period. They contain hormones - glucocorticosteroids, which quickly remove the symptoms and signs of inflammation. However, such drugs are recommended to be used only as directed by a doctor. Therefore, most patients often resort to alternative methods of combating the disease, especially during remission.
In severe forms of psoriasis, immunosuppressive drugs and cytostatics, glucocorticosteroids in tablets are prescribed.
Assigned for psoriasis also:
- vitamin complexes containing, in addition to vitamins A, E and D, zinc, magnesium and other trace elements,
- enzyme preparations for the digestive tract.
With an average degree of psoriasis, physiotherapy methods, especially PUVA therapy, have shown high efficiency. It consists in irradiating the skin with specially selected UV radiation and at the same time taking photosensitizing drugs. These drugs increase the effectiveness of exposure to skin radiation.
Solidol in the treatment of psoriasis
A good therapeutic effect in psoriasis is demonstrated by preparations containing solidol. This substance is a mixture of fatty acids. There are many recipes for ointments with solidol. The advantage of these drugs is their affordable price, low degree of allergenicity.
You can use pure solidol to lubricate the skin. However it should be
special solidol intended for medical use, not technical. The problem is that the technical solidol contains many additives that can harm the skin.
Check solidol for a possible allergic reaction is still worth it. To test on the inner surface of the elbow is applied a little solid oil. If in 12 hours there are no negative manifestations (redness, itching, swelling, etc.), then the drug can be used.
Solidol ointments are recommended for 2 to 4 weeks, they should be applied to the skin 1-2 times a day.
Pure solidol cannot be kept on the skin for a long time (unlike ointments with solidol). Procedures using this substance can begin with a 10-minute duration, gradually increasing this time by 10 minutes (after each week). Solidol must be washed off the skin with tar soap. Course duration - 3 months.
Pharmaceutical ointments containing solidol:
A method that can easily be observed by any patient with psoriasis at home is the right diet. After all, all processes occurring in the body are reflected on the skin. A wrong diet can disrupt the course of these processes. Therefore, some products are harmful to the skin, as it negatively affects its condition. There are even special diets, such as the Pegano diet, designed for psoriasis patients.
The essence of the Pegano diet is to find the right balance between acid-forming and alkali-forming foods. The first include meat and high-protein foods, legumes. The second - vegetables, fruits and cereals, with rare exceptions. The ratio of alkaline and acidic products, according to Pegano's theory, should be 4: 1.
It is also recommended to exclude from the menu:
- carbonated drinks,
- canned food and marinades,
- fried and smoked dishes.
Vegetable oils, low-fat sour-milk products must be present in the diet.
Treatment will be ineffective if you do not follow the basic rules of skin care. It is worth remembering that the skin with psoriasis has an increased sensitivity. Even a small cut or injection can lead to exacerbation, the appearance of psoriatic plaques. A similar phenomenon is called the Koebner phenomenon.
Skin care also includes:
- regular washing with mild hypoallergenic products,
- protecting the skin from excessive drying, hypothermia or overheating,
- wearing comfortable clothes made from natural materials,
- protection of hands from exposure to harsh household chemicals.
Climatic and spa treatment of psoriasis
Methods such as balneotherapy and spa treatment may also be useful in psoriasis. Sometimes an improvement can occur simply as a result of a change in climate to a warmer one. After all, as you know, exacerbations of psoriasis often occur in the cold season.
A stay at sea, even a short one, can be useful. Moist and clean sea air has a positive effect on the skin.
Medical baths are very popular for self-treatment of the disease. However, this method has contraindications. In particular, it is forbidden to take baths for people with cancer and heart failure.
The most commonly used therapeutic baths contain the following components:
Therapeutic baths with warm water and herbal extracts and infusions dissolved in them help relieve itching and inflammation of the skin, have a calming effect. Recommended bath time is 10-20 minutes. The optimum water temperature is about 38 ° C.
Baths with sea salt are best taken during remission for preventive purposes. The recommended number of procedures is 2-4 times a week. Sea salt contains various trace elements, such as potassium, magnesium and iodine, which have a beneficial effect on the skin condition.
Sports and outdoor activities
Exercise in sports and physical education per se does not affect the condition of the skin. However, they help strengthen the immune system and the body as a whole, relieve nervous tension.Since the disease is largely psychogenic in nature, these methods of therapy for many patients can also be useful.
Herbal medicine is a method used to treat various diseases from ancient times. With this technique, the role of drugs is played by various representatives of the flora. On the Internet you can find a huge number of recipes with medicinal plants, including those that help with psoriatic symptoms. Plants can be introduced into the composition of ointments, medicinal preparations for lotions, and can be taken orally in the form of decoctions.
However, caution must be exercised here. Indeed, among medicinal plants there are many allergens, and a number of them are contraindicated in cardiovascular diseases and gastrointestinal diseases. Therefore, before starting treatment with a prescription, it is advisable to consult a doctor.
If psoriatic plaques are observed on the scalp, then the main treatment can be supplemented with the use of therapeutic oils:
- sea buckthorn
- tea tree oil.
They are recommended to rub into the scalp. And sea buckthorn oil can be taken every day with a teaspoon.
Some effective homemade ointments
|Components||cooking method||frequency of use, once a day|
|celandine alcohol extract, linseed oil, petroleum jelly||the ratio of components is 2: 4: 1. The components are thoroughly mixed.||1|
|wood ash, solid oil, celandine, egg white||25 g of ash, 100 g of solidol, 1 egg white, 10 g of celandine are taken. The mixture is infused for 2 weeks||3|
|wormwood, melted pork fat||ratio of components 1: 1||3|
|propolis, butter||10 g of propolis, 200 g of butter. The mixture is heated over low heat for 15 minutes, then filtered||3|
|egg, sunflower oil, vinegar||2 eggs, 1 tbsp. l unrefined oil, 40 ml of vinegar. The mixture is whipped||1|
|birch tar, bee honey, petroleum jelly, fish oil, boric acid||ratio of components 25: 15: 10: 5: 5||1|
|elecampane roots, solidol||4 tbsp. l ground elecampane is poured into 100 g of hot water and held in a water bath for 15 minutes, filtered, cooled and mixed with 500 ml of solid oil||applied 2 times a day for 1 hour|
|solidol, honey, egg yolks||300 g of solid oil, 100 g of honey and 2 yolks are mixed||3 times a day for 2 hours|
Recipes decoctions of medicinal plants for oral administration
Many of psoriasis patients indicate stress as the root cause of the disease. And the disease itself is a source of additional stress.
There are different ways to deal with stress. However, some of them, such as alcohol or junk food, can only cause even more stress and problems.
Use those methods that really help to cope with stress and find harmony with yourself and others.
To prevent stress, use the following 9 steps:
- Plan time and do important things to the rest. Prepare for the upcoming stressful events: keep a positive attitude, rehearse the situation in advance, prepare a retreat plan. Eat a healthy diet. Exclude alcohol. Chat with friends and family. Be physically active for at least 30 minutes a day. Relax with yoga, for example. Meditate or use deep breathing for several minutes a day. If you experience uncontrolled anxiety or depression, be sure to seek medical help.
Sometimes even a telephone can help get rid of stress. In 2016, the AppStore had 902 stress-relieving apps. True, only 40 of them used scientifically based methods. The three main methods for controlling stress were: meditation and awareness, diaphragmatic breathing, and community support.
Meditation is one of the most effective methods for controlling stress. In the photo: hands of Buddha in a gesture of meditative concentration.
How long does psoriasis remission last as a result of the evolutionary approach?
The term "remission" is usually applied to chronic relapsing diseases. That is, remission involves another exacerbation after some time. Long-term remissions do not essentially differ from complete recovery.
Doctors say psoriasis cannot be cured. And this means that any remission will inevitably end and the disease will return again.
Representatives of the evolutionary approach argue:
By eliminating the causes of the disease, complete and infinitely long-term remission can be achieved. This means that psoriasis is treatable.
At least, the closer we get to the natural conditions of human existence in nature, the weaker the manifestations of psoriasis will be.
At the initial stage of following the evolutionary approach, you can resort to the help of medical methods. They will help relieve exacerbation and relieve itching and pain. And at the same time, we should continue to move towards eliminating the true causes of the disease. Then gradually the need for medical supplies will disappear.
The methods of the evolutionary approach, although they require time, effort and patience, are able to save not only psoriasis, but also other health problems.
Conclusions: limitations of the medical approach and the possibilities of evolutionary
You have come across many psoriasis treatments from the arsenal of medicine. Their plus is in the quick and complete elimination of the external manifestations of the ailment.
However, they have even more disadvantages, since these methods:
- lead only to temporary remission, because they do not affect the underlying causes of the disease, require accurate and prolonged use, as well as constant monitoring by the doctor, eventually lose their effectiveness, often lead to complications, sometimes so serious that they do not allow treatment to continue means, and they themselves require treatment, require great effort, time and money.
- natural and healthy food, clean water, the sun, natural and sufficient physical activity, healthy sleep, control of chronic stress.
Psoriasis factors and its symptoms
The study of psoriasis, its causes and the search for treatment continues. Until finally revealed the factors leading to skin damage. Experts emphasize the importance of the following points:
- significant activation of the rate of cell division, leading to exfoliation of the upper layer of the skin and the appearance of convex plaques,
- genetic predisposition
- weakening of the body's defenses (for example, after an illness).
The main distinguishing features of the disease make up a kind of triad, which includes:
- the formation of easily scraping scaly spots of whitish-gray color - the so-called phenomenon of stearin spot,
- further scraping reveals a smooth pink surface - the phenomenon of the terminal film,
- the appearance of blood droplets on a bare surface, or the phenomenon of point bleeding.
Since the disease is chronic, the question “How to cure psoriasis?” Automatically changes its wording to “How to transfer it to a long stage of remission?”
Local preparations reduce inflammation, peeling and the degree of skin infiltration. These are creams and ointments that contain the following components:
Glucocorticoid local drugs are also used. The use of lotions is advisable in the treatment of psoriasis with localization on the scalp.
- In the stage of disease progression, salicylic ointment or hormonal agents with an anti-inflammatory effect are prescribed. First, apply the lighter - prednisone, hydrocortisone. In the case of a repeated exacerbation, a significant severity of the inflammatory process, they are replaced by stronger fluorinated drugs: Sinalar, Celestoderm, Belosalik, Vipsogal.The use of these drugs is quite effective: in 70% of cases, as a result of 14-day use, it is possible to achieve a complete regression of rashes.
- For several years, non-halogenated glucocorticoids have been used: Elocom, Advantan. Due to the exclusion of chlorine and fluorine from their composition, the likelihood of adverse reactions of a local and systemic nature was significantly reduced. Drugs are the basis of local drug treatment of psoriasis in elderly patients and children.
- A pronounced effect is achieved with the use of ointments and creams with dithranol: cygnoderm, cygnoline, psorax. They are prescribed in increasing dosages according to short-term or long-term methods and have anti-inflammatory and anti-proliferative effects. Their minus is the likelihood of adverse reactions in the form of erythema, local swelling or itching.
- Today, a new drug, psorcutan, is used to treat psoriasis, which has a direct effect on pathogenetic factors that provoke the development of the disease. Its active component is calcipotriol, which enters into an active reaction with keratinocyte receptors and inhibits the process of their division, has immunocorrective and anti-inflammatory effects. Studies show that by the end of the second month the skin condition improves, the number of rashes is significantly reduced or they completely disappear. An important point is the absence of side effects in the form of skin atrophy, as well as the persistence of the result. Psorcutan is also used in the treatment of teardrop-shaped psoriasis, which is difficult to treat. In some cases, it is possible to achieve remission lasting up to one year. The effectiveness of the drug is significantly increased when combined with physiotherapy methods - PUVA or SFT irradiation.
Used tools must be changed periodically, because as a result of addiction, their effectiveness is reduced.
The basis of systemic therapy are aromatic retinoids (or synthetic derivatives of vitamin A). The 20-year practice of their use is proof of the effectiveness of these funds.
- Acetritin is an analogue of retinoic acid, does not provoke undesirable side effects and quickly eliminates them when they are provoked by aromatic retinoids. Acetrititis is the main active ingredient in tablets for the treatment of psoriasis - neotigazone.
- Cyclosporin A is prescribed in case of a complicated course of pathology.
- Methotrexate is a cytostatic agent (a substance that inhibits cell division). Its purpose is permissible only for severe varieties of the disease: arthropathic, pustular, erythroderma. Today, cytostatics are rarely used due to significant adverse reactions.
- Diclofenac, indomethacin - have an anti-inflammatory effect.
- Infliximab is one of the new treatments for psoriasis. The drug appeared recently, it belongs to the latest biotechnologies. At first it was used as a treatment for arthritis, as well as Crohn's disease, characterized by increased synthesis of tumor necrosis factor, or TNF. Since it is he who is the main link in the pathogenesis of psoriasis, experts drew attention to the appropriateness of its use for the treatment of this pathology. However, the drug leads to the appearance of a number of dangerous severe effects due to its powerful immunosuppressive effect:
- secondary infection
- increase the likelihood of developing tumors.
Treating Psoriatic Arthritis
The treatment of psoriatic arthritis is the task of two specialists: a rheumatologist and a dermatologist. The goal in this case is to achieve a state of remission (partial or complete). It should be noted that to stop the progression of the disease and eliminate symptoms can only be through the use of medications.Attempts by some patients to get rid of the disease in non-traditional ways do not lead to a positive result and can even provoke an exacerbation and complications in the form of serious changes in the tissues of the joints, spinal column, and some internal organs.
How can this form of psoriasis be cured? The medicines used are divided into two categories:
- symptomatic, which include anti-inflammatory non-steroidal drugs and glucocorticosteroids,
- basic medicines with anti-inflammatory effects: sulfasalazine, methotrexate, leflunomide.
The use of the first group leads to the rapid appearance of a positive result. Symptoms in the form of pain and stiffness disappear after a few hours. However, these medicines are not able to stop the process of destruction in the joints.
A more effective treatment for this type of psoriasis can be achieved through the use of basic drugs. The result of their action is manifested slowly, but the development of psoriatic arthritis in this case significantly slows down or even stops. The disadvantage of such medicines is that after a certain time the body gets used to them. It is necessary to increase the dose, which provokes the development of side effects.
An excellent result can be obtained through the use of anticytokine (biological) therapy, due to which it is possible to stop the destruction of the joints. Today, this method is considered the most effective.
A very important point is the timely start of treatment, when the joints have not yet undergone deformation, since this process is irreversible.
Palmar plantar psoriasis
How to cure a variety of psoriasis with localization on the palms and feet? This question is quite problematic, since traditional methods of therapy are ineffective, due to the significant degree of severity of pathological processes in the dermis and epidermis, as well as the factor of constant irritation and trauma to the skin of these areas as a result of contact with clothing, frequent washing, etc.
- For the treatment of palmar-plantar psoriasis to be effective, certain rules must be adhered to:
- Do not eat fried foods and spicy foods,
- quit smoking
- exclude alcoholic beverages,
- do not wash hands and feet with too hot water,
- use fabric-based household gloves to prevent contact with aggressive household chemicals,
- if cracks have formed on the feet, the use of a hydrocolloid solution is recommended: when applied to the affected areas, it prevents irritation from friction, relieves itching, and stimulates the restoration of the skin.
- The goal of pathogenetic therapy is to suppress the process of reproduction of keratinocytes, normalize their development, and reduce inflammation.
- External treatment consists in the use of:
- emollients and moisturizers that help remove the stratum corneum (in most cases, they are based on salicylic acid),
- Vitamin D derivatives
- If it is not possible to obtain a positive result, the so-called PUVA therapy is additionally applied, which in essence consists of irradiating the affected areas with ultraviolet rays using psoralen (a photoactive substance).
- With the ineffectiveness of other methods of treatment, systemic therapy is prescribed.
Elbow psoriasis treatment
This kind of pathology is treated comprehensively. This process is quite lengthy and includes:
- adherence to a special diet,
- intake of the vitamin complex,
- local treatment (ointments, creams, lotions),
- physiotherapeutic procedures
Treatment of mild forms of psoriasis on the elbows may be limited to the use of moisturizers, due to which it is possible to reduce peeling, to get rid of inflammation and itching.
With the advanced stage, complex treatment is used:
- local corticosteroid drugs,
- alternative methods of treating psoriasis (folk remedies).
Nail Psoriasis Treatment
The nail form of psoriasis was described in the 19th century. Even then, it was noted that it was isolated in nature, which subsequently received confirmation. Nails are affected in some types of psoriasis (for example, vulgar), but the disease can develop on its own.
How to treat nail psoriasis? The process is complex and time consuming. The disease has a recurrent nature, can occur in waves. The most important condition for therapy is proper nail and hand care, daily necessary measures and certain rules:
- nails should be cut short
- avoid microtrauma
- do not do manicures, pedicures, do not carry out other cosmetic procedures,
- wear household gloves while doing work.
To treat nail psoriasis in a mild form, medications are not used. It is possible to limit the application to the plate of medical varnish. They mask the affected areas, slow down the course of the pathological process and prevent relapses.
In severe cases, local treatment using ointments, solutions and creams is required. As an additional measure, it is recommended to take dietary supplements and vitamin formulations containing calcium, zinc, potassium, silicon. With an exacerbation of the process, it is better to refuse them.
Treatment of nail psoriasis at home includes:
- careful observance of the rules of hygiene of the hands and feet,
- taking calcium-containing drugs - they reduce the sensitivity of the nail tissue and have an anti-inflammatory effect,
- the use of antihistamines (tavegil, suprastin, etc.),
- baths based on a decoction of chamomile, sage, calendula, other medicinal plants,
- application of various oils to the affected plates: corn, olive, sunflower,
- intake of vitamins that improve metabolic processes at the cellular level.
Treatment of psoriasis of the scalp
- An important part of the treatment of psoriasis on the head is the intake of vitamins A and group B, preparations with calcium and nicotinic acid, and the use of ascorbic and folic acid.
- The most effective is the use of corticosteroid drugs.
- A good effect can be achieved using salicylic ointment.
- As an aid, it is recommended to moisten the scalp with decoctions of herbs with a pronounced anti-inflammatory effect: celandine, chamomile, or sage.
- Separately, it should be said about the Soderm solution, which many experts consider the most reliable way to get rid of psoriasis on the head. It is applied to the affected areas in the mornings and evenings. With a noticeable improvement, you can limit yourself to a single use of the drug, then use it every other day, etc.
Alternative methods for treating psoriasis on the head
Traditional medicine also offers many ways to get rid of this type of psoriasis.
- Compress based on celandine juice - relieves pain and inflammation.
- A series of alcoholic extract - should be taken orally three times a day for about 20 drops.
- A mask based on sea salt and clay (applied to the affected scalp).
Treatment of psoriasis on the face
Many patients try to hide traces of the lesion using cosmetics, but this can not be done. With constant contact with air and light exposure to sunlight, plaques heal much faster.
- A prerequisite for the treatment of psoriasis on the face is skin care, and you should use only products that are designed for sensitive skin.
- It is forbidden to wipe your face with a towel - this leads to mechanical damage to the plaques and stimulate their growth.
- In winter, you need to use moisturizers.
Complex therapy for the appearance of psoriasis on the face consists in the following measures:
- local treatment using ointments, creams, lotions,
- following a therapeutic diet,
- intake of vitamins.
Psoriatic plaques can spread to the area of eyelashes and eyebrows. In such cases, you can use lotion on the face using natural tissue soaked in warm saline. The procedure should be repeated several times a day. After it, the skin should be thoroughly dried.
With psoriasis on the face, you must avoid:
- exposure to dry air
- being in poorly ventilated or unventilated rooms,
- contact with chemical compounds, smoke,
- contact with skin of oils (including food).
How to protect your face
Since different factors affect the skin at different times of the year, recommendations vary depending on the season.
- In winter and autumn, it is necessary to protect the skin from rain, wind and cold. Protective equipment should be applied to it, do not forget about the hood and scarf.
- In warm seasons, the main focus should be on protection from the sun and high temperatures, although it should be noted that a moderate amount of ultraviolet radiation is very useful.
Dissolve a pack of salt in a bath of warm water, put the patient in it for 15 minutes. Moisten the scalp as well. After exiting the bath, a person should dry himself, without wiping. First, prepare the onion gruel and rub it into the patient’s head and body, leave it for about a quarter of an hour, remove the rest of the product with a rag and put the patient to bed. In the morning, you need to cook a celandine broth, boiling 300 grams of grass in a bucket of water, and wash your body with it. The next morning, wash with neutral soap and a weak solution of manganese. Repeat the procedure 7 times.
What is psoriasis?
This disease is attributed to non-infectious pathologies that are not able to be transmitted by household, sexual, airborne or any other route. Many patients believe that this disease only affects the skin, but this is not so. The ailment has several types, which can manifest itself not only on the skin, but also have a negative effect on nails, joints and some internal organs.
So what is psoriasis. In a person with healthy skin, the cycle of maturation and division of skin cells is from 28 to 30 days, with psoriasis, this period is reduced by tens of times and is only 4-6 days. Because of this, cells that have not yet matured begin to divide and die, as a result of which unpleasant white or grayish scales form on the skin. Scientists around the world still can not figure out the exact reasons why this process occurs. Only some provoking factors that can cause relapse and exacerbation of the pathology are known.
Most scientists tend to argue that psoriatic disease is an incurable disease and no one has yet succeeded in getting rid of it. It has also been known for a long time that it is impossible to cure psoriasis by any of the treatment methods. Sooner or later, the disease returns with renewed vigor.
The disease can occur in men, women and even children. According to some statistics, people living in countries with a cold and humid climate are more prone to illness. Also at risk are young people aged 18 to 25 years and older patients after 45-50 years of both sexes. Children are slightly less sick and their pathology can occur in an atypical form, those without symptoms characteristic of psoriasis, such as scales, itching and peeling.
What is the disease dangerous?
Do not assume that in addition to the aesthetic problem, psoriasis is not capable of causing serious harm to the body.Symptoms such as itching, redness, peeling - this is only a small part of what can provoke this ailment. Experts say that many patients often develop a form of the disease like psoriatic arthritis. This is a serious damage to the joints and cartilage, which can even lead to disability. The following manifestations can also be attributed to the complications of psoriasis:
- Damage and deformation of nails.
- Damage to the mucosa. It can also be a disease of the bladder and urethra.
- Against the background of the occurrence of pathology, serious diseases of the gastric mucosa can develop.
- Often the liver suffers, it increases in size and ceases to fulfill its functions.
- In addition, often patients experience complications such as epileptic seizures, depression, delirium, polyneuritis, and many other psychological disorders.
- Among the common complications are persistent muscle and joint pain, severe weight loss.
- Cases of myocardial infarction, strokes, heart failure and other diseases are known.
- Lymph nodes often enlarge, especially in the groin and hips.
These are just some of the consequences that the disease can lead to. The list goes on and on, but without this it is obvious that psoriasis is a serious disease that requires serious and timely treatment.
Causes of the development of the disease
At the present stage of the study of psoriasis, scientists and doctors have not been able to agree on the exact reasons for the development of the disease. Representatives of various theories adhere to points of view that explain the possible causes of the appearance of pathologically rapid division of skin cells. Next, we consider the most popular theories of the development of the disease.
This is one of the main and most reliable reasons for the appearance of the disease. Immunity is a natural human defense that can cope with many diseases. Sometimes, under the influence of various factors, immunity gives certain malfunctions. Representatives of this theory believe that psoriasis occurs as a result of an abnormal immune response to dermal cells. In other words, immune cells begin to attack skin cells, perceiving them as aggressors. As a result of this, severe itching, redness and inflammation occur.
Another point of view is genetic theory. Her supporters believe that psoriasis is inherited. According to medical statistics, more than 50% of all patients have a diseased pathology, one of the parents suffered from the disease. In addition, if the mother or father suffers from an ailment, the risk of developing psoriasis in a child increases by 25%, if both parents suffer from pathology, the risk increases by more than 50%.
The hormonal background of the body plays a very important role. The endocrine system, consisting of organs such as the thyroid, pancreas and pituitary gland, is fully responsible for the balance of hormones. Diseases and malfunctions of these organs can lead to hormonal imbalance, which, according to supporters of the endocrine theory, leads to the development of unhealthy cell division of the dermis.
Also, an imbalance can often occur during puberty, the menstrual cycle and menopause, as well as treatment with hormonal drugs and under the influence of some other reasons.
It is important to note that under the conditions of modern research, the effect of hormones on the occurrence of psoriasis has not been proved, so this theory remains only an assumption.
This is one of the young theories, whose representatives believe that the appearance of the disease can occur against the background of severe stress and psychosomatic disorders. The theory is also not proven, its supporters are conducting research to this day.
The neurogenic theory explains the appearance of the disease by the development of vasomotor neurosis in the walls and muscles of blood vessels.This process is able to cause narrowing of the vascular walls, resulting in significantly reduced blood circulation.
The theory is also not proven, however, numerous studies confirm the fact that in most patients psoriasis worsened or occurred for the first time after strong emotional stress and anxiety.
It is immediately worth noting that there is no direct relationship between viruses and psoriasis. It is only confirmed that after the transfer of certain diseases caused by the action of various viruses, psoriasis can worsen. Experts attribute this not to the viral origin of the pathology, but rather to the appearance of the disease against the background of a strong complication of the immune system.
In almost all patients with psoriasis, scientists identified the following deviations:
- The total body temperature of patients with pathology is slightly lower than in healthy people. This indicates a slowed down metabolic process.
- Another factor that unites all patients is an increase in blood cholesterol levels. As you know, the presence of large amounts of cholesterol in the blood can reduce the level of lipid metabolism. That is what can provoke the appearance on the skin of a person characteristic of the disease of the keratinized membrane of the dermis.
- Another unifying factor is a significant reduction in all patients of vitamins in the body. Most patients had a lack of B vitamins, however, interestingly, in the layers of the dermis, vitamin C was even present in excess.
What can trigger the development of the disease
Psoriasis disease and its treatment is a very complex process, which is often complicated by many provoking factors. These can be both external and internal influences that can provoke an exacerbation of a pathology or its initial appearance. So, the factors that can lead to the disease include:
- Psychosomatic disorders. Every day, many people experience a lot of stress and emotional stress. It can be problems at work, quarrels with relatives, loss of loved ones and much more. Answering the question of how to deal with psoriasis, doctors unanimously reiterate - try to avoid stress and nervous experiences.
- Another of the causes of the disease is the transfer of infectious diseases to the patient, as well as chronic inflammatory processes, as a result of advanced diseases. Also, the impetus for pathological processes in the skin may be the use of certain medications.
- Often the first rashes, as well as relapse, appear due to mechanical damage to the skin. Even a normal abrasion or scratch can cause serious skin problems.
- Disruption of the hormonal background is another serious reason that can provoke the disease.
- Treatment for psoriasis is impossible without giving up bad habits. Smoking and alcohol can cause rashes.
- Psoriasis can also be cured with a diet that excludes allergen products, as well as foods that contain large amounts of fat and carbohydrates.
Treatment for psoriasis is primarily the exclusion of factors that can exacerbate the disease. If the cause is not eliminated, psoriasis is almost impossible to cure.
This is one of the most common species. Many patients have encountered this problem and know how unpleasant this pathology is. Can head psoriasis be cured? Definitely not, like its other species. The disease manifests itself in each patient in different ways. These can be minor rashes in the area of the hairline, accompanied by peeling and dandruff, and the disease can manifest itself with large plaques with rough crusts and significant redness of the skin.
It is necessary to treat psoriasis of this type, it is categorically undesirable to let the disease drift.
Faced with this type of disease, patients are concerned about the question of whether nail psoriasis is being treated. After all, pathology not only significantly spoils the aesthetic appearance of the nail plates, but also leads to their strong distortion, exfoliation and even complete loss. This type of ailment develops most often against the background of other types of the disease and requires complex and proper treatment.
The fight against psoriasis of the nails often lies in an integrated approach and quite a long treatment. The patient must be patient to achieve positive results.
Hands, namely palms, are highly susceptible to various mechanical damage and friction. Often this type of disease occurs in both men and women. The main manifestations of psoriasis on the hands are corpus callosum with peeling, itching and redness. The disease is aggravated by frequent skin injuries, as the palms are very mobile.
Psoriasis on the face
The appearance of rashes on the face is very unpleasant, since this area is constantly in sight. Patients are puzzled by how to overcome facial psoriasis. After all, ugly flaky plaques not only cause severe discomfort at the physical level, but also a significant deterioration in the emotional state. A disease of this type can be deployed on any area of the face: cheeks, nose, lips, forehead and chin. The treatment of scaly lichen on the face (so called psoriasis) is a complex and troublesome process.
Psoriasis of the elbows
A frequent type of pathology, found in many patients of various age groups. It affects the outer surface of the elbows. Outwardly, the disease resembles the appearance on the skin of a whitish or grayish film in the form of a so-called carapace. Elbow psoriasis is not difficult to treat and often has favorable prognoses for patients.
Genital disease is quite rare. In almost 99% of cases, it is not an independent disease. Often the disease is confused with many sexually transmitted pathologies, and patients are in no hurry to consult a dermatologist. In men, the head of the penis is affected in women, the ailment extends to the labia.
Often develops after the transmission of viral and infectious diseases. Outwardly resembles small red drops that are framed by a whitish border. Often there are no peeling at all. The disease spreads to all parts of the body, can be a single rash or a large number of them.
Preparations for external use in psoriasis
Very often, for the purpose of relieving itching, inflammation, redness, and other symptoms of an ailment in medicine, means are used that are intended for external application. This group includes drugs produced in the form of ointments, gels, lotions, sprays, shampoos, foams and others.
The use of such drugs is indicated for mild and moderate forms of pathology. In cases of severe illness, such drugs are most often prescribed in combination with stronger drugs.
The specialist selects the medicine taking into account the severity of the disease and the individual characteristics of the patient. Methods of treating psoriasis with external drugs can be used in patients of different age categories and give a minimum of side effects.
The use of corticosteroids
One of the common groups of drugs for this disease are corticosteroids. They are fundamental in treatment and are used in most modern countries of the world. These drugs have the following effects:
- reduction in inflammation,
- slowing down the growth and division of dermal cells,
- elimination of an itch.
Corticosteroids can have strong and moderate effects. With severe degrees of the disease, a specialist prescribes drugs with a stronger effect, with milder forms - drugs with a mild effect.
By biological activity, drugs of this group can be divided into:
- low activity
- strong activity
- very strong.
Steroid preparations include the following:
- prednisone ointment.
Despite the rather good effectiveness of steroids, their use for most patients is insufficient. Doctors are forced to prescribe a comprehensive treatment, which includes the use of other medications.
Side effects of corticosteroids
When prescribing potent drugs related to this group, a specialist must necessarily take into account the risk of side effects. The negative manifestations include:
- the appearance of acne
- burning sensation and itching
- walls of blood vessels can expand,
- dry skin
- irritation and sensitivity of the skin.
Another serious drawback of steroids is the addictive effect. With prolonged use, the drug ceases to have the necessary effect and there is a loss of effectiveness. That is why doctors do not recommend patients to immediately take strong medicines.
Many patients wonder how to cure psoriasis and do vitamins play a role in the treatment? The answer to this question is unambiguously positive. The intake of vitamins during the disease is extremely necessary. Vitamin D3 is especially indicated for people with pathology. Studies on the use of drugs based on vitamin D3 have proven the good effectiveness of such drugs and the minimum number of side effects. These drugs include:
- tacalcitol and others.
Such agents are able to suspend excessively fast division of dermal cells, have anti-inflammatory effects. Their main distinguishing feature from corticosteroids is that the drugs are not addictive and have strong side effects. The union of steroids and drugs with vitamin D3 reduces the risk of complications, as they allow you to limit the concentration of active substances of steroid drugs. Quite good results are obtained with the use of ointments with vitamin D3, as well as herbal medicine.
Side Effects of Vitamin D3
Comprehensive treatment of psoriasis with vitamin D3 can also cause some side effects. These include:
- a decrease in vitamin D. This can interfere with normal bone growth, especially in children,
- increased calcium in the blood,
- irritation of the skin.
Take drugs should be strictly according to the scheme prescribed by a specialist. This will help to avoid many complications and unwanted side effects.
The use of retinoids
Medicines in this group contain vitamin A and are used to treat many skin diseases. So, how to treat psoriasis with the help of retinoids, we consider further. One of the first drugs that have proven themselves in psoriasis is tazarotene. It is used for mild to moderate severity of pathology. The drug is available in the form of external preparations, such as creams and gels.
Vitamin A products do not cause tolerance. Apply the product to the affected areas in small quantities. One of the contraindications is applying the cream to the genital area and eyelids.
Retinoids in combination with corticosteroids are quite effective.
It has long been known that psoriasis is not completely treated. However, complex and proper therapy can save a person from an illness for many years. One of the groups of drugs are systemic drugs. These are very serious drugs that are often used to treat severe autoimmune diseases, arthritis and oncology.
Such agents are administered predominantly orally or by injection. They are mainly used for especially severe forms of psoriasis, since systemic drugs have a number of serious side effects. Next, consider the most effective tools.The following drugs belong to systemic drugs:
Also, for the treatment of psoriasis, drugs are often used to treat diseases such as cancer, acne, and others. It can be:
- isotretinoin and others.
As you know, the disease can be complicated in the cold season, as well as in the summer months. Winter psoriasis, the treatment of which is often carried out with the help of light, responds quite well to therapy with PUVA. Photochemotherapy is one of the most effective modern methods. Thanks to this method, success can be achieved in more than 95% of cases. The action is to use long-wave ultraviolet treatment, as well as the introduction of photosensitizers into the body.
The use of PUVA is very effective in such types of pathology as exudative, vulgar, palmar-plantar psoriasis, as well as scalp disease. Photochemotherapy has proven itself very well in the treatment of severe forms such as pustular and erythrodermic psoriasis. Answering the question: is it possible to cure psoriasis using only light therapy, you can not give a definite answer. In most cases, treatment with physiotherapeutic methods still requires drug therapy.
Selective Phototherapy (SFT)
Using this method, the exudative and vulgar form of psoriasis is often treated. However, SFT is often used with a progressive form. Procedures are prescribed 5-6 times a week. Initial radiation doses are low, the doctor can increase them if the patient tolerates treatment well and there are no complications. The course of selective therapy averages 25-30 sessions.
Narrow-wave therapy (UVB)
No less effective than PUVA, gives excellent results in practice. The disadvantage is the high cost and inaccessibility of treatment, since today there is a shortage of equipment with which you can carry out UVB. In a week, the patient is shown 3-5 sessions, the general course is from 20 to 30 days.
Like other methods of therapy, phototherapy has a number of side effects. These include:
- dry skin
- itching and redness.
Some time after the application of light, side effects such as age spots may occur. Phototherapy should also be used very carefully because of frequent eye damage.
This is a relatively new method using the small fish Garra rufa. This type of therapy is carried out in sanatoriums where there are sources. The session is very simple. A person is immersed in water with fish, and those, in turn, cleanse the body of coarse particles of skin and scales, absolutely not affecting healthy areas.
Clay and mud treatment
Very well cleanses the skin of plaque healing mud. Often use, for example, the mud extracted on Lake Sivash. It can be purchased at the pharmacy. For application, the dirt is heated to a temperature of 38-39 degrees and applied in a thin layer to the affected areas. After 30-40 minutes, the mask is washed off with warm water and a softening cream is applied to the skin.
Massage for psoriasis is another effective method. Acupuncture is often used in conjunction with acupuncture. Massage for psoriasis has the following goals:
- General relaxation of the patient, the establishment of a psychosomatic state.
- Increased blood flow.
- Establishment of skin metabolic processes.
- Restoring skin integrity.
As already known, one of the main causes of psoriasis is a violation of the metabolic processes of the body. Due to imbalance in the balance of balance, an accumulation in the body of such negative products as toxins, toxins, and radicals occurs. These components have a very negative effect on the entire body, poisoning it from the inside.Blood transfusion for psoriasis is one of the methods to combat the disease. For these purposes, a centrifuge (plasmapheresis) is used. Using this method, you can clean the patient’s blood from harmful substances, as well as pathogenic viruses and fungi. Thanks to plasmapheresis, the following goals can be achieved:
- blood purification
- improved microcirculation,
- elimination of inflammation,
- elimination of decay products and other harmful components.
Alternative methods of treating the disease
Cleansing the body with psoriasis is often carried out using folk remedies. For these purposes, use various products of natural origin, as well as herbs. So, how to treat psoriasis using folk methods will be discussed later in the article.
All treatment methods can conditionally be divided into medicines for internal use, as well as funds for external application.
Prescription Drugs for Oral Administration
The following recipes are recommended to cleanse the skin and eliminate the main symptoms of psoriasis:
- Using flax seeds. To prepare the product, a tablespoon of seeds is poured with a glass of boiling water and thoroughly mixed. The drug must be infused for at least 12 hours. It is better to leave the medicine overnight. Take the infusion in the morning on an empty stomach.
- Laurel broth. A decoction of bay leaves has a good effect. To do this, add 10-15 medium leaves to a liter of boiling water and let the agent boil for 15-20 minutes over low heat. At the end, strain and cool. Take 1 tbsp. l three times a day for 20-30 days.
- Dill seeds. Plant seeds in an amount of 2 tbsp. l pour a glass of boiling water and insist 2-3 hours. After the medicine you need to strain and take half a glass 2-3 times a day.
- Tincture of herbs celandine. Celandine can be purchased at the pharmacy. For the preparation of 2 tbsp. l herbs fill in 500 g of alcohol and leave in a dark room for 10-12 days. After the remedy, it is necessary to strain and take 20 g three times a day.
Means for external use
The following recipes are used to get rid of plaques and cleanse the skin:
- Treatment of lesions with linseed oil. You can apply oil 5-6 times a day.
- Tar and propolis ointment. For cooking, you need to take 50 g of tar and 30 g of propolis. Products need to be heated in a water bath and mixed thoroughly. After cooling, apply the ointment to the plaques 3-4 times a day.
- It cleanses the skin very well fish oil in its pure form. It is applied to the affected areas with a thin layer and left for 30-40 minutes.
- Egg ointment. To prepare it, you need to take 2 chicken eggs and beat well. After add a spoonful of sesame or sea buckthorn oil and 40 g of vinegar. Ointment is applied to plaques 3-4 times throughout the day.
It is very important to follow a diet and other necessary preventive rules during the treatment of the disease. Prevention and treatment with the right means will help you get rid of the pathology for a long period.
Unfortunately, no way has yet been found to cure psoriasis forever. Therefore, patients with psoriasis are constantly looking for methods to increase pro.
To prolong remission in psoriasis, various methods are used - drug treatment, physiotherapy, and folk remedies. This disease is not contagious.
Psoriasis - this disease raises many questions in patients. Is it possible to wash with this skin pathology, visit saunas and pools? Are psorias compatible.
Many people know about the negative effect of alcohol on psoriasis, however, it is not reliably known whether psoriasis from alcohol can occur. It is believed that in.
Psoriasis is one of the most common dermatological diseases. Rashes can cover the entire body or individual areas. For ailment har.
Psoriasis refers to diseases that are very difficult to treat. It is impossible to completely get rid of an ailment. For quite a long time.
Many people have heard about psoriasis, but not everyone knows what psoriasis is and how to treat it. This disease is manifested by rashes on the skin and others very.
Today, psoriasis is one of the most common types among all dermatitis. The disease occurs in patients of various ages.
Causes and symptoms of the disease
Psoriasis is a disease that expresses itself very vividly. So, on the patient’s skin with an appropriate diagnosis, first appear single, and after - multiple relief convex inflamed reddish-pink spots. These rashes, in addition, are covered with a mass of silver-gray flakes, which are easily removed with the slightest mechanical impact.
In addition, psoriasis has long evolved from a medical into a psychological and even social problem. The thing is that the “updated” appearance of the affected skin becomes the cause of the onset of complexes, causes depressive states and causes the development of other forms of psycho-emotional disorders. In this regard, patients with psoriasis with a comprehensive fight against the disease visit the office of not only a dermatologist, but also a psychotherapist.
Of course, medical scientists put forward a lot of versions explaining the appearance of psoriatic plaques on the skin by the action of certain conditioning factors. So, the most popular theory of the origin of psoriasis is considered autoimmune. Its main idea is that psoriasis is a consequence of a hypertrophic attack by the body's defenses of healthy epidermal cells, as a result of which they begin to grow rapidly, multiply rapidly and transform into psoriatic foci that are familiar to the eye of any modern person.
Among other approaches to understanding the essence of psoriasis are popular:
- Metabolic (exchange)
- Endocrine (hormonal),
- Neurogenic (stressful),
This means that you can inherit not only the disease itself, but even a predisposition to the appearance of hated psoriatic plaques on the skin. So, according to the disappointing data of medical statistics, the risk of developing psoriasis in people whose relatives have already encountered this problem increases to 70-75%. Pathology can suddenly make itself known at any age against the background of an immune, endocrine or metabolic malfunction, or may be a consequence of an infectious (viral) disease.
The uncertainty of the etiology of psoriasis leads to the fact that there is no single universal treatment regimen that could help patients forget about this harmful disease forever. All therapeutic measures that dermatologists choose for their patients are exclusively symptomatic and are aimed at minimizing the inflammatory process, eliminating unpleasant sensations on the skin, and preventing complications and exacerbations of psoriasis.
The best pharmacy products to combat pathology
An effective treatment for psoriasis should be comprehensive. So, the standard treatment regimen for an ailment involves the use of systemic drugs of various spectrum of action, external psoriasis agents (gels, ointments, creams, sprays, shampoos with antibacterial, keratolytic, anti-inflammatory effects), physiotherapy and effective folk formulations (decoctions, infusions, tinctures based on medicinal plants).
The best treatment for psoriasis usually begins with local remedies. They help relieve inflammation, eliminate peeling and itching, effectively fight hyperemia and swelling, promote the rapid removal of psoriatic plaques from the skin and prevent the appearance of new rashes.
What effective remedy for psoriasis is preferred? A lot of local medicines (non-steroidal and hormonal) are sold in pharmacies, consider the most popular of them:
- Akriderm. Effective anti-inflammatory composition, used in short-term courses (no longer than 2 weeks). Relieves itching, peeling in the affected skin lesions. May be addictive.
- Another effective cure for psoriasis is Mesoderm. This is a hormonal ointment that is applied to psoriatic plaques twice a day, instantly relieves inflammation and discomfort on the skin. Like any drug containing glucocorticosteroids, it is used for short courses prescribed by a dermatologist.
- Dayvonex. The non-steroidal external composition, can be used on an ongoing basis, contains a synthetic analogue of vitamin D - calcipotriol. This drug eliminates signs of inflammation on the skin, relieves itching, peeling. It takes care of the “affected” dermis, launches the natural mechanisms of skin regeneration.
- Give free. Combined ointment with betamethasone and calcipotriol. It is applied no longer than 1 month (applied once a day to affected areas of the skin). This is the best remedy for psoriasis of the palm-plantar form, can not be applied sucking on the face and scalp.
- The most effective remedy for psoriasis in the non-steroidal group of drugs is Cartalin. This is a completely natural product based on solidol, does not contain hormonal components, so a long period of time can be used. This is the best cure for psoriasis with keratolytic, anti-inflammatory, and regenerative properties. Kartalin is applied to the affected skin lesions 1-2 times a day.
- Skin cap. Non-hormonal aerosol, based on it - zinc pyrithione. This external preparation shows an antibacterial effect, effectively fights inflammation, eliminates all the “local” symptoms of psoriasis. This medicine can also be found in the form of shampoo, cream, shower gel.
If external therapy for psoriasis does not lead to the desired result, patients with an appropriate diagnosis are selected systemic drugs of various spectrum of action. Consider what is better in this case to conduct an effective treatment of psoriasis:
- Methotrexate. It blocks hypertrophic attacks of the body's defenses aimed at healthy epidermal cells. The drug prevents the further spread of plaques throughout the body, does not allow abnormal rash elements to increase in size and multiply. It is taken in short courses, it can adversely affect the liver.
- Diprospan. Hormonal combination drug (injection). Provides a quick anti-inflammatory effect, actively combats the unpleasant symptoms of psoriasis on the skin. Dermatologists prescribe this drug only in extreme cases, with a severe course of the disease, since its use is associated with a lot of contraindications and side effects.
- Reamberin. The drug (injection), which removes all "pollutants" from the body - toxins, toxins. In addition, it is the most effective cure for psoriasis in terms of effects on metabolic processes. Reamberin ensures the timely supply of oxygen to the affected epidermal cells, improves their regeneration.
- Lycopid. The drug with an immunomodulating effect, has a positive effect on metabolism.
- Stelara. A drug used to combat psoriasis during an exacerbation of an ailment. The use of the drug is associated with a large number of side effects.
- Cyclosporin. Effective cytostatic, immunosuppressor. This drug fights off the body's immune attacks aimed at healthy skin cells, and also reduces the rate of propagation of the rash elements and prevents them from further spreading through the body of patients with psoriasis.Cyclosporin is taken in short courses under the supervision of a dermatologist - the drug gives a load on the digestive tract. During treatment, patients are prohibited from staying in direct sunlight for a long time.
Alternative therapy of the disease
It is advisable to supplement the medical treatment of psoriasis with effective decoctions, infusions, tinctures based on medicinal plants. As well as homemade ointments, creams and other compositions of hand-made cooking.
Of course, according to dermatologists, the use of these mixtures is intended to provide only an auxiliary symptomatic effect on the body, but still you should not refuse them.
Consider several useful recipes that can be used in a comprehensive home fight against psoriasis:
- 20 chicken eggs are boiled for 20 minutes in boiling water, then they are peeled, the protein is separated from the yolk, the latter is fried in a dry frying pan without oil for 45 minutes at low heat. The finished mass is wrapped in cheesecloth, squeezed out - the psoriatic plaques are treated with the resulting liquid twice a day until the skin is completely cleansed of the rashes.
- Affected areas of the skin can be lubricated daily with pickled cabbage brine - an excellent anti-inflammatory and antibacterial agent.
- A small amount of castor oil is impregnated with a cotton swab, pockets of psoriasis are treated. After two to three hours, this area of the skin is washed with running water and soap. Manipulations are repeated daily for 2 weeks.
- Fat technical solidol is an effective remedy for psoriasis. Before starting treatment, it is necessary to conduct an allergic test - apply a small amount of the product to a small area of the skin, wait half an hour, see if a rash appears. If no abnormal manifestations are found, you can start local therapy: first, densely treat psoriatic foci with a solidol daily, and after 15 minutes wash off this home remedy with tar soap. After a week and a half, you can increase the duration of the procedure up to 1 hour. The total duration of treatment is 1-1.5 months.
The general therapeutic scheme is selected by dermatologists for each person with an appropriate diagnosis, taking into account the mass of factors - form, type, severity and stage of psoriasis, age, general health, individual characteristics of the body, etc. Only a competent specialist after a comprehensive examination can correctly choose the tactics treatment of such a complex systemic disease as psoriasis.